| Back to Multiple platform build/check report for BioC 3.22: simplified long | 
  | 
This page was generated on 2025-11-03 12:03 -0500 (Mon, 03 Nov 2025).
| Hostname | OS | Arch (*) | R version | Installed pkgs | 
|---|---|---|---|---|
| nebbiolo2 | Linux (Ubuntu 24.04.3 LTS) | x86_64 | 4.5.1 Patched (2025-08-23 r88802) -- "Great Square Root" | 4902 | 
| lconway | macOS 12.7.6 Monterey | x86_64 | 4.5.1 Patched (2025-09-10 r88807) -- "Great Square Root" | 4692 | 
| kjohnson3 | macOS 13.7.7 Ventura | arm64 | 4.5.1 Patched (2025-09-10 r88807) -- "Great Square Root" | 4638 | 
| Click on any hostname to see more info about the system (e.g. compilers) (*) as reported by 'uname -p', except on Windows and Mac OS X | ||||
| Package 606/2361 | Hostname | OS / Arch | INSTALL | BUILD | CHECK | BUILD BIN | ||||||||
| DMRcaller 1.42.0  (landing page) Nicolae Radu Zabet 
  | nebbiolo2 | Linux (Ubuntu 24.04.3 LTS) / x86_64 | OK | OK | OK | |||||||||
| lconway | macOS 12.7.6 Monterey / x86_64 | OK | OK | OK | OK | |||||||||
| kjohnson3 | macOS 13.7.7 Ventura / arm64 | OK | OK | OK | OK | |||||||||
| 
To the developers/maintainers of the DMRcaller package: - Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/DMRcaller.git to reflect on this report. See Troubleshooting Build Report for more information. - Use the following Renviron settings to reproduce errors and warnings. - If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.  | 
| Package: DMRcaller | 
| Version: 1.42.0 | 
| Command: /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:DMRcaller.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings DMRcaller_1.42.0.tar.gz | 
| StartedAt: 2025-11-02 20:53:08 -0500 (Sun, 02 Nov 2025) | 
| EndedAt: 2025-11-02 21:02:23 -0500 (Sun, 02 Nov 2025) | 
| EllapsedTime: 555.4 seconds | 
| RetCode: 0 | 
| Status: OK | 
| CheckDir: DMRcaller.Rcheck | 
| Warnings: 0 | 
##############################################################################
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### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:DMRcaller.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings DMRcaller_1.42.0.tar.gz
###
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* using log directory ‘/Users/biocbuild/bbs-3.22-bioc/meat/DMRcaller.Rcheck’
* using R version 4.5.1 Patched (2025-09-10 r88807)
* using platform: x86_64-apple-darwin20
* R was compiled by
    Apple clang version 14.0.0 (clang-1400.0.29.202)
    GNU Fortran (GCC) 14.2.0
* running under: macOS Monterey 12.7.6
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘DMRcaller/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘DMRcaller’ version ‘1.42.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘DMRcaller’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... NOTE
Packages listed in more than one of Depends, Imports, Suggests, Enhances:
  ‘GenomicRanges’ ‘S4Vectors’ ‘IRanges’ ‘betareg’
A package should be listed in only one of these fields.
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... NOTE
Namespaces in Imports field not imported from:
  ‘BiocManager’ ‘GenomeInfoDb’ ‘Seqinfo’
  All declared Imports should be used.
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
.validateModif: no visible global function definition for ‘seqlengths’
extractGC: no visible global function definition for ‘seqlevels’
readONTbam: no visible binding for global variable
  ‘BSgenome.Hsapiens.UCSC.hg38’
readONTbam: no visible global function definition for ‘seqlengths’
selectCytosine: no visible binding for global variable
  ‘BSgenome.Hsapiens.UCSC.hg38’
selectCytosine : <anonymous>: no visible global function definition for
  ‘seqlengths’
selectCytosine : <anonymous>: no visible global function definition for
  ‘seqlevels<-’
selectCytosine : <anonymous>: no visible global function definition for
  ‘seqlengths<-’
selectCytosine: no visible global function definition for ‘seqlevels<-’
selectCytosine: no visible global function definition for ‘seqlevels’
Undefined global functions or variables:
  BSgenome.Hsapiens.UCSC.hg38 seqlengths seqlengths<- seqlevels
  seqlevels<-
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... NOTE
Found the following Rd file(s) with Rd \link{} targets missing package
anchors:
  analyseReadsInsideRegionsForCondition.Rd: GRanges
  computeDMRs.Rd: GRanges
  computeMethylationDataCoverage.Rd: GRanges
  computeMethylationProfile.Rd: GRanges
  computeOverlapProfile.Rd: GRanges
  computeVMDs.Rd: GRanges
  extractGC.Rd: GRanges
  filterDMRs.Rd: GRanges
  filterVMDs.Rd: GRanges
  getWholeChromosomes.Rd: GRanges
  mergeDMRsIteratively.Rd: GRanges
  plotLocalMethylationProfile.Rd: GRanges, GRangesList
  plotMethylationDataCoverage.Rd: GRanges
  plotMethylationProfile.Rd: GRanges
  plotMethylationProfileFromData.Rd: GRanges
  plotOverlapProfile.Rd: GRanges
  poolMethylationDatasets.Rd: GRangesList, GRanges
  poolTwoMethylationDatasets.Rd: GRanges
  readBismark.Rd: GRanges
  readBismarkPool.Rd: GRanges
  saveBismark.Rd: GRanges
Please provide package anchors for all Rd \link{} targets not in the
package itself and the base packages.
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... OK
* checking data for ASCII and uncompressed saves ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                       user system elapsed
computePMDs          62.694  0.328  63.075
filterVMDs           23.273  0.116  23.405
computeDMRs           8.384  0.118   8.510
mergeDMRsIteratively  7.930  0.098   8.034
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘runTests.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE
Status: 4 NOTEs
See
  ‘/Users/biocbuild/bbs-3.22-bioc/meat/DMRcaller.Rcheck/00check.log’
for details.
DMRcaller.Rcheck/00install.out
############################################################################## ############################################################################## ### ### Running command: ### ### /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL DMRcaller ### ############################################################################## ############################################################################## * installing to library ‘/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library’ * installing *source* package ‘DMRcaller’ ... ** this is package ‘DMRcaller’ version ‘1.42.0’ ** using staged installation ** R ** data ** inst ** byte-compile and prepare package for lazy loading ** help *** installing help indices ** building package indices ** installing vignettes ** testing if installed package can be loaded from temporary location ** testing if installed package can be loaded from final location ** testing if installed package keeps a record of temporary installation path * DONE (DMRcaller)
DMRcaller.Rcheck/tests/runTests.Rout
R version 4.5.1 Patched (2025-09-10 r88807) -- "Great Square Root"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin20
R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.
R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.
> BiocGenerics:::testPackage("DMRcaller")
Attaching package: 'generics'
The following objects are masked from 'package:base':
    as.difftime, as.factor, as.ordered, intersect, is.element, setdiff,
    setequal, union
Attaching package: 'BiocGenerics'
The following objects are masked from 'package:stats':
    IQR, mad, sd, var, xtabs
The following objects are masked from 'package:base':
    Filter, Find, Map, Position, Reduce, anyDuplicated, aperm, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, is.unsorted, lapply,
    mapply, match, mget, order, paste, pmax, pmax.int, pmin, pmin.int,
    rank, rbind, rownames, sapply, saveRDS, table, tapply, unique,
    unsplit, which.max, which.min
Attaching package: 'S4Vectors'
The following object is masked from 'package:utils':
    findMatches
The following objects are masked from 'package:base':
    I, expand.grid, unname
Parameters checking ...
Using user-specified core count: 1
Current parallel setting, BPPARAM: 
class: SerialParam
  bpisup: FALSE; bpnworkers: 1; bptasks: 2147483647; bpjobname: BPJOB
  bplog: FALSE; bpthreshold: INFO; bpstopOnError: TRUE
  bpRNGseed: ; bptimeout: NA; bpprogressbar: TRUE
  bpexportglobals: FALSE; bpexportvariables: FALSE; bpforceGC: FALSE
  bpfallback: FALSE
  bplogdir: NA
  bpresultdir: NA
Extract methylation in the corresponding context 
Loading required namespace: GenomeInfoDb
Computing DMRs 
Merge adjacent DMRs
Merge DMRs iteratively
Filter DMRs 
Parameters checking ...
Current parallel setting, BPPARAM: 
class: SerialParam
  bpisup: FALSE; bpnworkers: 1; bptasks: 2147483647; bpjobname: BPJOB
  bplog: FALSE; bpthreshold: INFO; bpstopOnError: TRUE
  bpRNGseed: ; bptimeout: NA; bpprogressbar: TRUE
  bpexportglobals: FALSE; bpexportvariables: FALSE; bpforceGC: FALSE
  bpfallback: FALSE
  bplogdir: NA
  bpresultdir: NA
Extract methylation in the corresponding context 
Computing DMRs at  Chr1:1..4976 
Calculating interpolations...
Identifying DMRs...
Analysed reads inside DMRs
Merge DMRs iteratively
Filter DMRs 
Parameters checking ...
Current parallel setting, BPPARAM: 
class: SerialParam
  bpisup: FALSE; bpnworkers: 1; bptasks: 2147483647; bpjobname: BPJOB
  bplog: FALSE; bpthreshold: INFO; bpstopOnError: TRUE
  bpRNGseed: ; bptimeout: NA; bpprogressbar: TRUE
  bpexportglobals: FALSE; bpexportvariables: FALSE; bpforceGC: FALSE
  bpfallback: FALSE
  bplogdir: NA
  bpresultdir: NA
Extract methylation in the corresponding context 
Computing DMRs at  Chr1:1..4976 
Selecting data...
Identifying DMRs...
Validating objects 
Finding overlaps 
Joining objects 
Parameters checking ...
Using user-specified core count: 1
Current parallel setting, BPPARAM: 
class: SerialParam
  bpisup: FALSE; bpnworkers: 1; bptasks: 2147483647; bpjobname: BPJOB
  bplog: FALSE; bpthreshold: INFO; bpstopOnError: TRUE
  bpRNGseed: ; bptimeout: NA; bpprogressbar: TRUE
  bpexportglobals: FALSE; bpexportvariables: FALSE; bpforceGC: FALSE
  bpfallback: FALSE
  bplogdir: NA
  bpresultdir: NA
Extract methylation in the corresponding context 
Computing DMRs at  Chr1:1..4976 
Count inside each bin...
Filter the bins...
Identifying DMRs...
Merge adjacent DMRs
Merge DMRs iteratively
Filter DMRs 
Parameters checking ...
Current parallel setting, BPPARAM: 
class: SerialParam
  bpisup: FALSE; bpnworkers: 1; bptasks: 2147483647; bpjobname: BPJOB
  bplog: FALSE; bpthreshold: INFO; bpstopOnError: TRUE
  bpRNGseed: ; bptimeout: NA; bpprogressbar: TRUE
  bpexportglobals: FALSE; bpexportvariables: FALSE; bpforceGC: FALSE
  bpfallback: FALSE
  bplogdir: NA
  bpresultdir: NA
Merge DMRs iteratively ...
Loading required package: GenomeInfoDb
Loading required package: BSgenome
Loading required package: Biostrings
Loading required package: XVector
Attaching package: 'Biostrings'
The following object is masked from 'package:base':
    strsplit
Loading required package: BiocIO
Loading required package: rtracklayer
Parameters checking ...
Parameters checking ...
Select the Cytosine Positions in the specified BSgenome ...
Current parallel setting, BPPARAM: 
class: SerialParam
  bpisup: FALSE; bpnworkers: 1; bptasks: 2147483647; bpjobname: BPJOB
  bplog: FALSE; bpthreshold: INFO; bpstopOnError: TRUE
  bpRNGseed: ; bptimeout: NA; bpprogressbar: TRUE
  bpexportglobals: FALSE; bpexportvariables: FALSE; bpforceGC: FALSE
  bpfallback: FALSE
  bplogdir: NA
  bpresultdir: NA
[readONTbam] Generating index file for BAM ...
[readONTbam] Loading BAM ...
Step 1 (scanBam): 0.10 sec
[readONTbam] Filtering invalid or empty reads ...
Step 2 (filter): 0.19 sec
[readONTbam] Generating cytosine position list and indel_info ...
[readONTbam] Start Decoding MM/ML ...
  |                                                                            
  |                                                                      |   0%[readONTbam] Decoding MM/ML: 20% (1/5 reads)
  |                                                                            
  |==============                                                        |  20%[readONTbam] Decoding MM/ML: 40% (2/5 reads)
  |                                                                            
  |============================                                          |  40%[readONTbam] Decoding MM/ML: 60% (3/5 reads)
  |                                                                            
  |==========================================                            |  60%[readONTbam] Decoding MM/ML: 80% (4/5 reads)
  |                                                                            
  |========================================================              |  80%[readONTbam] Decoding MM/ML: 100% (5/5 reads)
  |                                                                            
  |======================================================================| 100%
Step 3 (decode Bam file): 5.70 sec
[readONTbam] Calculating overlaps with reference cytosines ...
Step 4 (coverage): 3.42 sec
[readONTbam] Annotating high-confidence modified reads ...
Step 5 (ONT_Cm & readsM meta-column): 1.01 sec
[readONTbam] Annotating unmodified (covered) reads & Calculating coverage per position...
Step 6 (ONT_C & readsN meta-column): 0.81 sec
[readONTbam] Done. Returning annotated GRanges.
Total: 11.23 sec
RUNIT TEST PROTOCOL -- Sun Nov  2 21:02:13 2025 
*********************************************** 
Number of test functions: 7 
Number of errors: 0 
Number of failures: 0 
 
1 Test Suite : 
DMRcaller RUnit Tests - 7 test functions, 0 errors, 0 failures
Number of test functions: 7 
Number of errors: 0 
Number of failures: 0 
There were 36 warnings (use warnings() to see them)
> 
> proc.time()
   user  system elapsed 
131.407   2.400 134.095 
DMRcaller.Rcheck/DMRcaller-Ex.timings
| name | user | system | elapsed | |
| DMRcaller | 0.001 | 0.003 | 0.003 | |
| analyseReadsInsideRegionsForCondition | 1.027 | 0.030 | 1.058 | |
| analyseReadsInsideRegionsForConditionPMD | 0.534 | 0.025 | 0.560 | |
| computeCoMethylatedPositions | 0 | 0 | 0 | |
| computeCoMethylatedRegions | 0.279 | 0.008 | 0.287 | |
| computeDMRs | 8.384 | 0.118 | 8.510 | |
| computeDMRsReplicates | 0 | 0 | 0 | |
| computeMethylationDataCoverage | 0.324 | 0.053 | 0.389 | |
| computeMethylationDataSpatialCorrelation | 1.041 | 0.063 | 1.104 | |
| computeMethylationProfile | 0.932 | 0.046 | 0.981 | |
| computeOverlapProfile | 1.273 | 0.047 | 1.323 | |
| computePMDs | 62.694 | 0.328 | 63.075 | |
| computeVMDs | 0.000 | 0.000 | 0.001 | |
| extractGC | 0.000 | 0.000 | 0.001 | |
| filterDMRs | 1.387 | 0.066 | 1.455 | |
| filterPMDs | 1.513 | 0.047 | 1.561 | |
| filterVMDs | 23.273 | 0.116 | 23.405 | |
| filterVMRsONT | 0.001 | 0.001 | 0.001 | |
| getWholeChromosomes | 0.125 | 0.007 | 0.133 | |
| joinReplicates | 0.423 | 0.049 | 0.474 | |
| mergeDMRsIteratively | 7.930 | 0.098 | 8.034 | |
| mergePMDsIteratively | 3.234 | 0.008 | 3.243 | |
| plotLocalMethylationProfile | 1.428 | 0.110 | 1.540 | |
| plotMethylationDataCoverage | 0.640 | 0.044 | 0.688 | |
| plotMethylationDataSpatialCorrelation | 0.675 | 0.093 | 0.775 | |
| plotMethylationProfile | 0.804 | 0.070 | 0.877 | |
| plotMethylationProfileFromData | 2.245 | 0.155 | 2.406 | |
| plotOverlapProfile | 1.383 | 0.013 | 1.399 | |
| poolMethylationDatasets | 0.398 | 0.046 | 0.447 | |
| poolTwoMethylationDatasets | 0.413 | 0.092 | 0.510 | |
| readBismark | 1.425 | 0.110 | 1.555 | |
| readBismarkPool | 3.206 | 0.274 | 3.495 | |
| readONTbam | 0 | 0 | 0 | |
| saveBismark | 1.044 | 0.048 | 1.129 | |
| selectCytosine | 0.000 | 0.001 | 0.002 | |