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This page was generated on 2025-11-13 11:32 -0500 (Thu, 13 Nov 2025).

HostnameOSArch (*)R versionInstalled pkgs
kjohnson3macOS 13.7.7 Venturaarm64R Under development (unstable) (2025-11-04 r88984) -- "Unsuffered Consequences" 4013
Click on any hostname to see more info about the system (e.g. compilers)      (*) as reported by 'uname -p', except on Windows and Mac OS X

Package 1485/2325HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
OmnipathR 3.19.0  (landing page)
Denes Turei
Snapshot Date: 2025-11-12 13:40 -0500 (Wed, 12 Nov 2025)
git_url: https://git.bioconductor.org/packages/OmnipathR
git_branch: devel
git_last_commit: 44ae7c7
git_last_commit_date: 2025-10-29 10:55:03 -0500 (Wed, 29 Oct 2025)
kjohnson3macOS 13.7.7 Ventura / arm64  OK    OK    ERROR    OK  


CHECK results for OmnipathR on kjohnson3

To the developers/maintainers of the OmnipathR package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/OmnipathR.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.

raw results


Summary

Package: OmnipathR
Version: 3.19.0
Command: /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:OmnipathR.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings OmnipathR_3.19.0.tar.gz
StartedAt: 2025-11-12 19:43:50 -0500 (Wed, 12 Nov 2025)
EndedAt: 2025-11-12 20:03:12 -0500 (Wed, 12 Nov 2025)
EllapsedTime: 1162.1 seconds
RetCode: 1
Status:   ERROR  
CheckDir: OmnipathR.Rcheck
Warnings: NA

Command output

##############################################################################
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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:OmnipathR.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings OmnipathR_3.19.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/Users/biocbuild/bbs-3.23-bioc/meat/OmnipathR.Rcheck’
* using R Under development (unstable) (2025-11-04 r88984)
* using platform: aarch64-apple-darwin20
* R was compiled by
    Apple clang version 16.0.0 (clang-1600.0.26.6)
    GNU Fortran (GCC) 14.2.0
* running under: macOS Ventura 13.7.8
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘OmnipathR/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘OmnipathR’ version ‘3.19.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... INFO
Imports includes 35 non-default packages.
Importing from so many packages makes the package vulnerable to any of
them becoming unavailable.  Move as many as possible to Suggests and
use conditionally.
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘OmnipathR’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking whether startup messages can be suppressed ... NOTE
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:06] [INFO]    [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 19:44:06] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-11-12 19:44:06] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-11-12
[2025-11-12 19:44:06] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.6.0; ; 2025-11-12 20:19:41 UTC; unix
[2025-11-12 19:44:06] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.19.0
[2025-11-12 19:44:06] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.23
[2025-11-12 19:44:06] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-11-04 r88984); os=macOS Ventura 13.7.8; system=aarch64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-11-12; pandoc=3.1.12.3 @ /opt/homebrew/bin/ (via rmarkdown); quarto=1.7.32 @ /usr/local/bin/quarto]
[2025-11-12 19:44:06] [INFO]    [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; zstd=1.5.5; PCRE=10.44 2024-06-07; ICU=70.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libR.dylib; readline=5.2; BLAS=/System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1]
[2025-11-12 19:44:06] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); digest 0.6.38(2025-11-12); dplyr 1.1.4(2023-11-17); evaluate 1.0.5(2025-08-27); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); glue 1.8.0(2024-09-30); hms 1.1.4(2025-10-17); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.2.1(2025-10-27); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); memoise 2.0.1(2021-11-26); OmnipathR 3.19.0(2025-11-12); otel 0.2.0(2025-08-29); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.5.0(2025-11-01); ps 1.9.1(2025-04-12); purrr 1.2.0(2025-11-04); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.1.0(2025-07-02); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.30(2025-09-28); RSQLite 2.4.4(2025-11-10); rvest 1.0.5(2025-08-29); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.6.0(2025-11-04); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.54(2025-10-30); XML 3.99-0.20(2025-11-08); xml2 1.4.1(2025-10-27); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13)
[2025-11-12 19:44:06] [INFO]    [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: aarch64-apple-darwin23.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Contains 1 files.
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:06] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Pandoc version: `3.1.12.3`.
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:06] [TRACE]   [OmnipathR] Cache locked: FALSE

It looks like this package (or a package it requires) has a startup
message which cannot be suppressed: see ?packageStartupMessage.
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:19] [INFO]    [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 19:44:19] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-11-12 19:44:19] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-11-12
[2025-11-12 19:44:19] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.6.0; ; 2025-11-12 20:19:41 UTC; unix
[2025-11-12 19:44:19] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.19.0
[2025-11-12 19:44:19] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.23
[2025-11-12 19:44:19] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-11-04 r88984); os=macOS Ventura 13.7.8; system=aarch64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-11-12; pandoc=3.1.12.3 @ /opt/homebrew/bin/ (via rmarkdown); quarto=1.7.32 @ /usr/local/bin/quarto]
[2025-11-12 19:44:19] [INFO]    [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; zstd=1.5.5; PCRE=10.44 2024-06-07; ICU=70.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libR.dylib; readline=5.2; BLAS=/System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1]
[2025-11-12 19:44:19] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); digest 0.6.38(2025-11-12); dplyr 1.1.4(2023-11-17); evaluate 1.0.5(2025-08-27); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); glue 1.8.0(2024-09-30); hms 1.1.4(2025-10-17); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.2.1(2025-10-27); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); memoise 2.0.1(2021-11-26); OmnipathR 3.19.0(2025-11-12); otel 0.2.0(2025-08-29); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.5.0(2025-11-01); ps 1.9.1(2025-04-12); purrr 1.2.0(2025-11-04); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.1.0(2025-07-02); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.30(2025-09-28); RSQLite 2.4.4(2025-11-10); rvest 1.0.5(2025-08-29); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.6.0(2025-11-04); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.54(2025-10-30); XML 3.99-0.20(2025-11-08); xml2 1.4.1(2025-10-27); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13)
[2025-11-12 19:44:19] [INFO]    [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: aarch64-apple-darwin23.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Contains 1 files.
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:19] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Pandoc version: `3.1.12.3`.
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 19:44:19] [TRACE]   [OmnipathR] Cache locked: FALSE
.cosmos_pkn: no visible global function definition for
  ‘metabolite_idsc’
cosmos_ksn: no visible binding for global variable
  ‘substrate_genesymbol’
cosmos_ksn: no visible binding for global variable ‘residue_type’
cosmos_ksn: no visible binding for global variable ‘residue_offset’
cosmos_ksn: no visible binding for global variable ‘enzyme_genesymbol’
cosmos_ksn: no visible binding for global variable ‘mor’
recon3d_compartments: no visible global function definition for
  ‘.slow_dowtest’
recon3d_genes: no visible global function definition for
  ‘.slow_dowtest’
recon3d_genes: no visible binding for global variable ‘notes’
recon3d_genes: no visible binding for global variable ‘annotation’
recon3d_genes: no visible binding for global variable
  ‘original_bigg_ids’
recon3d_metabolites: no visible global function definition for
  ‘.slow_dowtest’
recon3d_metabolites: no visible binding for global variable ‘notes’
recon3d_metabolites: no visible binding for global variable
  ‘original_bigg_ids’
recon3d_metabolites: no visible binding for global variable
  ‘annotation’
recon3d_metabolites: no visible binding for global variable ‘hmdb’
recon3d_metabolites: no visible binding for global variable ‘metHMDBID’
recon3d_raw: no visible global function definition for ‘.slow_dowtest’
recon3d_raw_vmh: no visible global function definition for
  ‘.slow_dowtest’
recon3d_reactions: no visible global function definition for
  ‘.slow_dowtest’
recon3d_reactions: no visible binding for global variable ‘notes’
recon3d_reactions: no visible binding for global variable ‘metabolites’
recon3d_reactions: no visible binding for global variable
  ‘original_bigg_ids’
recon3d_table: no visible global function definition for
  ‘.slow_dowtest’
taxon_names_table: no visible binding for global variable
  ‘latin_name_uniprot’
taxon_names_table: no visible binding for global variable
  ‘latin_name_ensembl’
taxon_names_table: no visible binding for global variable
  ‘latin_name_oma’
taxon_names_table: no visible binding for global variable
  ‘common_name_ensembl’
taxon_names_table: no visible binding for global variable
  ‘common_name_uniprot’
Undefined global functions or variables:
  .slow_dowtest annotation common_name_ensembl common_name_uniprot
  enzyme_genesymbol hmdb latin_name_ensembl latin_name_oma
  latin_name_uniprot metHMDBID metabolite_idsc metabolites mor notes
  original_bigg_ids residue_offset residue_type substrate_genesymbol
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking R/sysdata.rda ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... ERROR
Running examples in ‘OmnipathR-Ex.R’ failed
The error most likely occurred in:

> base::assign(".ptime", proc.time(), pos = "CheckExEnv")
> ### Name: recon3d_metabolites
> ### Title: Metabolites from Recon-3D
> ### Aliases: recon3d_metabolites recon3d_reactions recon3d_genes
> ###   recon3d_compartments
> 
> ### ** Examples
> 
> recon3d_metabolites()
Error in .slow_dowtest() : could not find function ".slow_dowtest"
Calls: recon3d_metabolites
Execution halted
Examples with CPU (user + system) or elapsed time > 5s
                                       user system elapsed
annotation_categories                40.176  0.078  43.024
curated_ligrec_stats                 15.704  2.184  93.809
omnipath-interactions                13.873  1.345  51.098
filter_extra_attrs                   10.479  4.555  36.462
all_uniprots                          8.881  1.616 287.493
extra_attrs_to_cols                   7.437  1.519  14.800
nichenet_gr_network_omnipath          6.677  0.797  12.373
go_annot_download                     6.591  0.516   7.423
extra_attr_values                     5.129  1.201  16.649
extra_attrs                           4.625  1.525   7.735
filter_by_resource                    5.358  0.349   8.528
pivot_annotations                     5.289  0.375  20.747
giant_component                       4.874  0.501  11.449
nichenet_signaling_network_omnipath   4.682  0.499  11.020
omnipath_for_cosmos                   4.277  0.347  26.870
has_extra_attrs                       2.812  1.016   8.024
filter_intercell                      3.214  0.230   8.826
print_interactions                    3.124  0.263   9.359
curated_ligand_receptor_interactions  2.746  0.537  14.836
ensembl_id_mapping_table              1.533  0.147  20.300
ensembl_organisms                     0.779  0.334  12.757
ensembl_organisms_raw                 0.755  0.351  72.084
kegg_conv                             0.652  0.082  10.790
metalinksdb_sqlite                    0.557  0.132  10.424
kinasephos                            0.458  0.069  19.846
kegg_link                             0.337  0.049   6.229
kegg_rm_prefix                        0.339  0.040   5.657
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 1 ERROR, 2 NOTEs
See
  ‘/Users/biocbuild/bbs-3.23-bioc/meat/OmnipathR.Rcheck/00check.log’
for details.


Installation output

OmnipathR.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL OmnipathR
###
##############################################################################
##############################################################################


* installing to library ‘/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library’
* installing *source* package ‘OmnipathR’ ...
** this is package ‘OmnipathR’ version ‘3.19.0’
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
*** copying figures
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
[2025-11-12 15:19:46] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 15:19:46] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:46] [INFO]    [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 15:19:46] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-11-12 15:19:46] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-11-12
[2025-11-12 15:19:46] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.6.0; ; 2025-11-12 20:19:41 UTC; unix
[2025-11-12 15:19:46] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.19.0
[2025-11-12 15:19:46] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.23
[2025-11-12 15:19:46] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-11-04 r88984); os=macOS Ventura 13.7.8; system=aarch64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-11-12; pandoc=3.1.12.3 @ /opt/homebrew/bin/ (via rmarkdown); quarto=1.7.32 @ /usr/local/bin/quarto]
[2025-11-12 15:19:47] [INFO]    [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; zstd=1.5.5; PCRE=10.44 2024-06-07; ICU=70.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libR.dylib; readline=5.2; BLAS=/System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1]
[2025-11-12 15:19:47] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); digest 0.6.38(2025-11-12); dplyr 1.1.4(2023-11-17); evaluate 1.0.5(2025-08-27); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); glue 1.8.0(2024-09-30); hms 1.1.4(2025-10-17); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.2.1(2025-10-27); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); memoise 2.0.1(2021-11-26); OmnipathR 3.19.0(2025-11-12); otel 0.2.0(2025-08-29); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.5.0(2025-11-01); ps 1.9.1(2025-04-12); purrr 1.2.0(2025-11-04); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.1.0(2025-07-02); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.30(2025-09-28); RSQLite 2.4.4(2025-11-10); rvest 1.0.5(2025-08-29); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.6.0(2025-11-04); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.54(2025-10-30); XML 3.99-0.20(2025-11-08); xml2 1.4.1(2025-10-27); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13)
[2025-11-12 15:19:47] [INFO]    [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: aarch64-apple-darwin23.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Contains 1 files.
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:47] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Pandoc version: `3.1.12.3`.
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/00LOCK-OmnipathR/00new/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/00LOCK-OmnipathR/00new/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/00LOCK-OmnipathR/00new/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/00LOCK-OmnipathR/00new/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Cache locked: FALSE
** testing if installed package can be loaded from final location
[2025-11-12 15:19:47] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:48] [INFO]    [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 15:19:48] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-11-12 15:19:48] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-11-12
[2025-11-12 15:19:48] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.6.0; ; 2025-11-12 20:19:41 UTC; unix
[2025-11-12 15:19:48] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.19.0
[2025-11-12 15:19:48] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.23
[2025-11-12 15:19:48] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-11-04 r88984); os=macOS Ventura 13.7.8; system=aarch64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-11-12; pandoc=3.1.12.3 @ /opt/homebrew/bin/ (via rmarkdown); quarto=1.7.32 @ /usr/local/bin/quarto]
[2025-11-12 15:19:48] [INFO]    [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; zstd=1.5.5; PCRE=10.44 2024-06-07; ICU=70.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libR.dylib; readline=5.2; BLAS=/System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1]
[2025-11-12 15:19:48] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); digest 0.6.38(2025-11-12); dplyr 1.1.4(2023-11-17); evaluate 1.0.5(2025-08-27); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); glue 1.8.0(2024-09-30); hms 1.1.4(2025-10-17); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.2.1(2025-10-27); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); memoise 2.0.1(2021-11-26); OmnipathR 3.19.0(2025-11-12); otel 0.2.0(2025-08-29); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.5.0(2025-11-01); ps 1.9.1(2025-04-12); purrr 1.2.0(2025-11-04); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.1.0(2025-07-02); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.30(2025-09-28); RSQLite 2.4.4(2025-11-10); rvest 1.0.5(2025-08-29); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.6.0(2025-11-04); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.54(2025-10-30); XML 3.99-0.20(2025-11-08); xml2 1.4.1(2025-10-27); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13)
[2025-11-12 15:19:48] [INFO]    [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: aarch64-apple-darwin23.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Contains 1 files.
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:48] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Pandoc version: `3.1.12.3`.
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 15:19:48] [TRACE]   [OmnipathR] Cache locked: FALSE
** testing if installed package keeps a record of temporary installation path
* DONE (OmnipathR)

Tests output

OmnipathR.Rcheck/tests/testthat.Rout


R Under development (unstable) (2025-11-04 r88984) -- "Unsuffered Consequences"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: aarch64-apple-darwin20

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> #!/usr/bin/env Rscript
> 
> #
> #  This file is part of the `OmnipathR` R package
> #
> #  Copyright
> #  2018-2024
> #  Saez Lab, Uniklinik RWTH Aachen, Heidelberg University
> #
> #  File author(s): Alberto Valdeolivas
> #                  Dénes Türei (turei.denes@gmail.com)
> #                  Attila Gábor
> #
> #  Distributed under the MIT (Expat) License.
> #  See accompanying file `LICENSE` or find a copy at
> #      https://directory.fsf.org/wiki/License:Expat
> #
> #  Website: https://r.omnipathdb.org/
> #  Git repo: https://github.com/saezlab/OmnipathR
> #
> 
> 
> library(testthat)
> library(OmnipathR)
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 20:00:13] [INFO]    [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 20:00:13] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-11-12 20:00:13] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-11-12
[2025-11-12 20:00:13] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.6.0; ; 2025-11-12 20:19:41 UTC; unix
[2025-11-12 20:00:13] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.19.0
[2025-11-12 20:00:13] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.23
[2025-11-12 20:00:13] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-11-04 r88984); os=macOS Ventura 13.7.8; system=aarch64, darwin20; ui=X11; language=C; collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-11-12; pandoc=3.1.12.3 @ /opt/homebrew/bin/ (via rmarkdown); quarto=1.7.32 @ /usr/local/bin/quarto]
[2025-11-12 20:00:13] [INFO]    [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; zstd=1.5.5; PCRE=10.44 2024-06-07; ICU=70.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libR.dylib; readline=5.2; BLAS=/System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1]
[2025-11-12 20:00:13] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); brio 1.1.5(2024-04-24); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); digest 0.6.38(2025-11-12); dplyr 1.1.4(2023-11-17); evaluate 1.0.5(2025-08-27); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); glue 1.8.0(2024-09-30); hms 1.1.4(2025-10-17); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.2.1(2025-10-27); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); memoise 2.0.1(2021-11-26); OmnipathR 3.19.0(2025-11-12); otel 0.2.0(2025-08-29); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.5.0(2025-11-01); ps 1.9.1(2025-04-12); purrr 1.2.0(2025-11-04); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.1.0(2025-07-02); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.30(2025-09-28); RSQLite 2.4.4(2025-11-10); rvest 1.0.5(2025-08-29); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.6.0(2025-11-04); testthat 3.2.3(2025-01-13); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.54(2025-10-30); XML 3.99-0.20(2025-11-08); xml2 1.4.1(2025-10-27); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13)
[2025-11-12 20:00:13] [INFO]    [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: aarch64-apple-darwin23.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Contains 11 files.
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 20:00:13] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Pandoc version: `3.1.12.3`.
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.6-arm64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-11-12 20:00:13] [TRACE]   [OmnipathR] Cache locked: FALSE
> 
> test_check('OmnipathR')
[ FAIL 0 | WARN 12 | SKIP 0 | PASS 38 ]

[ FAIL 0 | WARN 12 | SKIP 0 | PASS 38 ]
> 
> proc.time()
   user  system elapsed 
 17.902   2.891 171.237 

Example timings

OmnipathR.Rcheck/OmnipathR-Ex.timings

nameusersystemelapsed
OmnipathR000
all_uniprot_acs0.0060.0010.008
all_uniprots 8.881 1.616287.493
ancestors0.0040.0010.005
annotated_network0.5930.0643.876
annotation_categories40.176 0.07843.024
annotation_resources0.0470.0070.575
annotations0.2730.0271.374
biomart_query0.6040.0833.639
bioplex10.0040.0010.012
bioplex20.0040.0010.021
bioplex30.0080.0020.026
bioplex_all0.0040.0010.023
bioplex_hct116_10.0040.0010.005
bma_motif_es0.2820.0401.370
bma_motif_vs0.0780.0130.764
chalmers_gem0.0030.0010.003
chalmers_gem_id_mapping_table0.0040.0010.017
chalmers_gem_id_type0.0010.0000.002
chalmers_gem_metabolites0.0030.0010.007
chalmers_gem_network0.0040.0010.026
chalmers_gem_raw0.0040.0010.028
chalmers_gem_reactions0.0030.0010.005
common_name0.0500.0040.126
complex_genes0.3260.0352.385
complex_resources0.0230.0050.647
complexes0.0770.0100.742
consensuspathdb_download0.0000.0000.001
consensuspathdb_raw_table0.0060.0010.008
cosmos_pkn000
curated_ligand_receptor_interactions 2.746 0.53714.836
curated_ligrec_stats15.704 2.18493.809
database_summary0.8170.1073.254
descendants0.0040.0010.005
ensembl_dataset0.0240.0020.038
ensembl_id_mapping_table 1.533 0.14720.300
ensembl_id_type0.0000.0000.001
ensembl_name0.1180.0060.176
ensembl_organisms 0.779 0.33412.757
ensembl_organisms_raw 0.755 0.35172.084
ensembl_orthology000
enzsub_graph0.9110.0914.365
enzsub_resources0.0210.0040.529
enzyme_substrate0.4270.0291.281
evex_download0.0020.0000.002
evidences000
extra_attr_values 5.129 1.20116.649
extra_attrs4.6251.5257.735
extra_attrs_to_cols 7.437 1.51914.800
filter_by_resource5.3580.3498.528
filter_extra_attrs10.479 4.55536.462
filter_intercell3.2140.2308.826
filter_intercell_network0.0080.0020.041
find_all_paths2.4370.1933.632
from_evidences000
get_db000
get_ontology_db0.0050.0010.051
giant_component 4.874 0.50111.449
go_annot_download6.5910.5167.423
go_annot_slim000
go_ontology_download0.0040.0010.026
guide2pharma_download0.0040.0010.013
harmonizome_download0.0030.0010.011
has_extra_attrs2.8121.0168.024
hmdb_id_mapping_table0.0040.0010.015
hmdb_id_type0.0010.0000.003
hmdb_metabolite_fields0.0000.0000.001
hmdb_protein_fields000
hmdb_table0.0030.0010.006
homologene_download0.0030.0010.003
homologene_raw0.0230.0010.036
homologene_uniprot_orthology0.0030.0010.029
hpo_download1.4620.1452.296
htridb_download0.0060.0010.009
id_translation_resources000
id_types0.0300.0040.034
inbiomap_download000
inbiomap_raw000
interaction_datasets0.3570.0340.820
interaction_graph0.1730.0210.960
interaction_resources0.0230.0050.507
interaction_types0.0260.0040.044
intercell0.3830.0561.882
intercell_categories0.2960.0380.724
intercell_consensus_filter0.6650.0753.064
intercell_generic_categories0.0330.0030.076
intercell_network0.0040.0010.004
intercell_resources0.0230.0040.594
intercell_summary0.0310.0090.085
is_ontology_id000
is_swissprot0.0200.0020.037
is_trembl0.0200.0020.038
is_uniprot0.0030.0010.005
kegg_api_templates0.0000.0010.001
kegg_conv 0.652 0.08210.790
kegg_databases000
kegg_ddi0.2640.0351.805
kegg_find0.2750.0332.146
kegg_info0.0030.0010.010
kegg_link0.3370.0496.229
kegg_list0.2880.0372.033
kegg_open0.0030.0010.004
kegg_operations000
kegg_organism_codes0.0080.0290.075
kegg_organisms0.0080.0040.019
kegg_pathway_annotations0.0000.0010.000
kegg_pathway_download0.0050.0010.024
kegg_pathway_list0.0030.0010.004
kegg_pathways_download000
kegg_picture0.5480.0254.564
kegg_process0.0070.0020.013
kegg_query0.0030.0000.006
kegg_request0.0280.0050.096
kegg_rm_prefix0.3390.0405.657
kinasephos 0.458 0.06919.846
latin_name0.0960.0060.138
load_db0.0250.0090.051
metalinksdb_sqlite 0.557 0.13210.424
metalinksdb_table0.0940.0180.172
metalinksdb_tables0.0080.0010.030
ncbi_taxid0.1000.0080.114
nichenet_build_model000
nichenet_expression_data0.0030.0010.004
nichenet_gr_network0.0100.0030.017
nichenet_gr_network_evex0.0030.0010.003
nichenet_gr_network_harmonizome0.0030.0010.013
nichenet_gr_network_htridb0.0060.0010.038
nichenet_gr_network_omnipath 6.677 0.79712.373
nichenet_gr_network_pathwaycommons0.0030.0010.005
nichenet_gr_network_regnetwork0.0030.0000.003
nichenet_gr_network_remap0.0030.0010.010
nichenet_gr_network_trrust0.0030.0010.005
nichenet_ligand_activities000
nichenet_ligand_target_links000
nichenet_ligand_target_matrix000
nichenet_lr_network0.0080.0020.018
nichenet_lr_network_guide2pharma0.0040.0010.025
nichenet_lr_network_omnipath0.0360.0020.050
nichenet_lr_network_ramilowski0.0030.0010.003
nichenet_main0.0000.0000.001
nichenet_networks0.0150.0050.067
nichenet_optimization000
nichenet_remove_orphan_ligands0.0090.0020.021
nichenet_results_dir000
nichenet_signaling_network0.0090.0020.014
nichenet_signaling_network_cpdb0.0030.0010.005
nichenet_signaling_network_evex0.0030.0010.004
nichenet_signaling_network_harmonizome0.0030.0010.006
nichenet_signaling_network_inbiomap000
nichenet_signaling_network_omnipath 4.682 0.49911.020
nichenet_signaling_network_pathwaycommons0.0040.0010.008
nichenet_signaling_network_vinayagam0.0020.0000.003
nichenet_test000
nichenet_workarounds000
obo_parser0.0330.0070.160
oma_code0.0540.0030.060
oma_organisms0.0520.0080.075
oma_pairwise0.0030.0010.005
oma_pairwise_genesymbols0.0030.0010.004
oma_pairwise_translated0.0030.0010.004
omnipath-interactions13.873 1.34551.098
omnipath_cache_autoclean000
omnipath_cache_clean0.0220.0030.026
omnipath_cache_clean_db0.0480.0130.065
omnipath_cache_download_ready0.2170.0710.335
omnipath_cache_filter_versions0.0410.0130.071
omnipath_cache_get0.0290.0100.041
omnipath_cache_key0.0010.0000.000
omnipath_cache_latest_or_new0.0270.0080.038
omnipath_cache_load0.2090.0232.643
omnipath_cache_move_in0.0700.0170.146
omnipath_cache_remove0.0260.0100.056
omnipath_cache_save0.0440.0110.099
omnipath_cache_search0.0000.0010.001
omnipath_cache_set_ext0.0260.0100.078
omnipath_cache_update_status0.0280.0080.071
omnipath_cache_wipe000
omnipath_config_path0.0000.0000.001
omnipath_for_cosmos 4.277 0.34726.870
omnipath_load_config000
omnipath_log0.0000.0000.001
omnipath_logfile0.0010.0000.000
omnipath_msg0.0010.0000.002
omnipath_query1.7900.1122.359
omnipath_reset_config000
omnipath_save_config000
omnipath_set_cachedir0.0100.0030.044
omnipath_set_console_loglevel0.0010.0000.002
omnipath_set_logfile_loglevel0.0010.0000.001
omnipath_set_loglevel0.0000.0000.001
omnipath_show_db0.0200.0050.077
omnipath_unlock_cache_db000
only_from000
ontology_ensure_id000
ontology_ensure_name000
ontology_name_id0.0010.0000.001
organism_for0.0650.0040.099
pathwaycommons_download0.0010.0000.000
pivot_annotations 5.289 0.37520.747
preppi_download000
preppi_filter000
print_bma_motif_es0.2830.0371.070
print_bma_motif_vs0.0580.0110.737
print_interactions3.1240.2639.359
print_path_es0.3730.0412.182
print_path_vs1.0950.1584.749
pubmed_open2.5460.1442.780
query_info0.2200.0180.556
ramilowski_download000
ramp_id_mapping_table000
ramp_id_type0.0010.0010.001
ramp_sqlite000
ramp_table0.0010.0000.001
ramp_tables000