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### Running command:
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###   /Library/Frameworks/R.framework/Resources/bin/R CMD build --keep-empty-dirs --no-resave-data MOFA2
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* checking for file ‘MOFA2/DESCRIPTION’ ... OK
* preparing ‘MOFA2’:
* checking DESCRIPTION meta-information ... OK
* installing the package to build vignettes
* creating vignettes ... ERROR
--- re-building ‘MEFISTO_temporal.Rmd’ using rmarkdown

Attaching package: 'MOFA2'

The following object is masked from 'package:stats':

    predict

── Attaching packages ─────────────────────────────────────── tidyverse 1.3.1 ──
✔ ggplot2 3.3.6     ✔ purrr   0.3.4
✔ tibble  3.1.7     ✔ dplyr   1.0.9
✔ tidyr   1.2.0     ✔ stringr 1.4.0
✔ readr   2.1.2     ✔ forcats 0.5.1
── Conflicts ────────────────────────────────────────── tidyverse_conflicts() ──
✖ dplyr::filter() masks stats::filter()
✖ dplyr::lag()    masks stats::lag()
Checking data options...
Checking training options...
Warning in prepare_mofa(sm, model_options = model_opts, mefisto_options = mefisto_opts,  :
  Maximum number of iterations is very small

Checking model options...
Checking inference options for mefisto covariates...
Connecting to the mofapy2 python package using reticulate (use_basilisk = FALSE)... 
    Please make sure to manually specify the right python binary when loading R with reticulate::use_python(..., force=TRUE) or the right conda environment with reticulate::use_condaenv(..., force=TRUE)
    If you prefer to let us automatically install a conda environment with 'mofapy2' installed using the 'basilisk' package, please use the argument 'use_basilisk = TRUE'

Warning in run_mofa(sm, outfile) :
  mofapy2_0.6.4 is not detected in the specified python binary, see reticulate::py_config(). Setting use_basilisk = TRUE...
Connecting to the mofapy2 package using basilisk. 
    Set 'use_basilisk' to FALSE if you prefer to manually set the python binary using 'reticulate'.
Quitting from lines 96-98 (MEFISTO_temporal.Rmd) 
Error: processing vignette 'MEFISTO_temporal.Rmd' failed with diagnostics:
one node produced an error: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.9.2/MOFA2/1.7.0/mofa_env/lib/libpython3.7m.dylib - dlopen(/Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.9.2/MOFA2/1.7.0/mofa_env/lib/libpython3.7m.dylib, 0x000A): tried: '/Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.9.2/MOFA2/1.7.0/mofa_env/lib/libpython3.7m.dylib' (mach-o file, but is an incompatible architecture (have 'x86_64', need 'arm64e'))
--- failed re-building ‘MEFISTO_temporal.Rmd’

--- re-building ‘downstream_analysis.Rmd’ using rmarkdown
Warning in for (i in ind) init <- forceAndCall(2, f, init, x[[i]]) :
  closing unused connection 5 (<-localhost:11377)
Registered S3 method overwritten by 'GGally':
  method from   
  +.gg   ggplot2
--- finished re-building ‘downstream_analysis.Rmd’

--- re-building ‘getting_started_R.Rmd’ using rmarkdown

Attaching package: 'data.table'

The following objects are masked from 'package:dplyr':

    between, first, last

The following object is masked from 'package:purrr':

    transpose

Creating MOFA object from a list of matrices (features as rows, sample as columns)...

Creating MOFA object from a list of matrices (features as rows, sample as columns)...

Checking data options...
Checking training options...
Checking model options...
Quitting from lines 213-215 (getting_started_R.Rmd) 
Error: processing vignette 'getting_started_R.Rmd' failed with diagnostics:
one node produced an error: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.9.2/MOFA2/1.7.0/mofa_env/lib/libpython3.7m.dylib - dlopen(/Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.9.2/MOFA2/1.7.0/mofa_env/lib/libpython3.7m.dylib, 0x000A): tried: '/Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.9.2/MOFA2/1.7.0/mofa_env/lib/libpython3.7m.dylib' (mach-o file, but is an incompatible architecture (have 'x86_64', need 'arm64e'))
--- failed re-building ‘getting_started_R.Rmd’

SUMMARY: processing the following files failed:
  ‘MEFISTO_temporal.Rmd’ ‘getting_started_R.Rmd’

Error: Vignette re-building failed.
Execution halted