Back to Multiple platform build/check report for BioC 3.22: simplified long |
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This page was generated on 2025-09-22 12:04 -0400 (Mon, 22 Sep 2025).
Hostname | OS | Arch (*) | R version | Installed pkgs |
---|---|---|---|---|
nebbiolo2 | Linux (Ubuntu 24.04.3 LTS) | x86_64 | 4.5.1 Patched (2025-08-23 r88802) -- "Great Square Root" | 4814 |
lconway | macOS 12.7.1 Monterey | x86_64 | 4.5.1 Patched (2025-09-10 r88807) -- "Great Square Root" | 4603 |
kjohnson3 | macOS 13.7.7 Ventura | arm64 | 4.5.1 Patched (2025-09-10 r88807) -- "Great Square Root" | 4547 |
taishan | Linux (openEuler 24.03 LTS) | aarch64 | 4.5.0 (2025-04-11) -- "How About a Twenty-Six" | 4553 |
Click on any hostname to see more info about the system (e.g. compilers) (*) as reported by 'uname -p', except on Windows and Mac OS X |
Package 879/2333 | Hostname | OS / Arch | INSTALL | BUILD | CHECK | BUILD BIN | ||||||||
gINTomics 1.5.0 (landing page) Angelo Velle
| nebbiolo2 | Linux (Ubuntu 24.04.3 LTS) / x86_64 | OK | OK | ERROR | |||||||||
lconway | macOS 12.7.1 Monterey / x86_64 | OK | OK | ERROR | OK | |||||||||
kjohnson3 | macOS 13.7.7 Ventura / arm64 | OK | OK | ERROR | OK | |||||||||
taishan | Linux (openEuler 24.03 LTS) / aarch64 | OK | OK | TIMEOUT | ||||||||||
To the developers/maintainers of the gINTomics package: - Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/gINTomics.git to reflect on this report. See Troubleshooting Build Report for more information. - Use the following Renviron settings to reproduce errors and warnings. - If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information. |
Package: gINTomics |
Version: 1.5.0 |
Command: /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:gINTomics.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings gINTomics_1.5.0.tar.gz |
StartedAt: 2025-09-21 21:25:26 -0400 (Sun, 21 Sep 2025) |
EndedAt: 2025-09-21 21:54:55 -0400 (Sun, 21 Sep 2025) |
EllapsedTime: 1768.4 seconds |
RetCode: 1 |
Status: ERROR |
CheckDir: gINTomics.Rcheck |
Warnings: NA |
############################################################################## ############################################################################## ### ### Running command: ### ### /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:gINTomics.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings gINTomics_1.5.0.tar.gz ### ############################################################################## ############################################################################## * using log directory ‘/Users/biocbuild/bbs-3.22-bioc/meat/gINTomics.Rcheck’ * using R version 4.5.1 Patched (2025-09-10 r88807) * using platform: x86_64-apple-darwin20 * R was compiled by Apple clang version 14.0.0 (clang-1400.0.29.202) GNU Fortran (GCC) 14.2.0 * running under: macOS Monterey 12.7.6 * using session charset: UTF-8 * using option ‘--no-vignettes’ * checking for file ‘gINTomics/DESCRIPTION’ ... OK * this is package ‘gINTomics’ version ‘1.5.0’ * package encoding: UTF-8 * checking package namespace information ... OK * checking package dependencies ... INFO Imports includes 42 non-default packages. Importing from so many packages makes the package vulnerable to any of them becoming unavailable. Move as many as possible to Suggests and use conditionally. * checking if this is a source package ... OK * checking if there is a namespace ... OK * checking for hidden files and directories ... OK * checking for portable file names ... OK * checking for sufficient/correct file permissions ... OK * checking whether package ‘gINTomics’ can be installed ... OK * checking installed package size ... OK * checking package directory ... OK * checking ‘build’ directory ... OK * checking DESCRIPTION meta-information ... OK * checking top-level files ... OK * checking for left-over files ... OK * checking index information ... OK * checking package subdirectories ... OK * checking code files for non-ASCII characters ... OK * checking R files for syntax errors ... OK * checking whether the package can be loaded ... OK * checking whether the package can be loaded with stated dependencies ... OK * checking whether the package can be unloaded cleanly ... OK * checking whether the namespace can be loaded with stated dependencies ... OK * checking whether the namespace can be unloaded cleanly ... OK * checking dependencies in R code ... OK * checking S3 generic/method consistency ... OK * checking replacement functions ... OK * checking foreign function calls ... OK * checking R code for possible problems ... NOTE [2025-09-21 21:29:50] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:29:50] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:29:50] [INFO] [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 21:29:50] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 21:29:50] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 21:29:50] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 21:29:50] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 21:29:50] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 21:29:51] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 21:29:51] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 21:29:52] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); DelayedArray 0.35.3(2025-09-21); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggplot2 4.0.0(2025-09-11); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); gtable 0.3.6(2024-10-25); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); OmnipathR 3.17.4(2025-09-21); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); SparseArray 1.9.1(2025-09-21); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); viridisLite 0.4.2(2023-05-02); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13) [2025-09-21 21:29:52] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE [2025-09-21 21:29:52] [TRACE] [OmnipathR] Running on a build server, wiping cache. [2025-09-21 21:29:52] [TRACE] [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 21:29:52] [TRACE] [OmnipathR] Contains 1 files. [2025-09-21 21:29:52] [TRACE] [OmnipathR] Cache is locked: FALSE. [2025-09-21 21:29:52] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:29:52] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:29:52] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 21:29:52] [TRACE] [OmnipathR] Pandoc version: `2.7.3`. [2025-09-21 21:29:52] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8). [2025-09-21 21:29:52] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:29:52] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8). [2025-09-21 21:29:52] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:29:52] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8). [2025-09-21 21:29:52] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:29:52] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8). [2025-09-21 21:29:52] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:29:52] [TRACE] [OmnipathR] Cache locked: FALSE .build_histo: no visible binding for global variable ‘chr_cov’ .build_histo: no visible binding for global variable ‘significance’ .build_ridge: no visible binding for global variable ‘coef’ .build_ridge: no visible binding for global variable ‘significance’ .circos_preprocess: no visible binding for global variable ‘cnv_met’ .find_deg: no visible global function definition for ‘combn’ .find_deg: no visible global function definition for ‘contrasts.fit’ .prepare_cnv_heatmap: no visible binding for global variable ‘cnv’ .prepare_gen_heatmap: no visible binding for global variable ‘met’ .prepare_gen_heatmap: no visible binding for global variable ‘cnv’ .prepare_met_heatmap: no visible binding for global variable ‘met’ .prepare_mirna_heatmap: no visible binding for global variable ‘mirna_cnv’ .prepare_network: no visible binding for global variable ‘omics’ .prepare_reactive_histo_tf: no visible binding for global variable ‘Freq’ .prepare_reactive_venn: no visible binding for global variable ‘cnv_met’ .prepare_reactive_venn: no visible binding for global variable ‘pval’ .reactive_cnv_test_plots: no visible binding for global variable ‘x’ .reactive_cnv_test_plots: no visible binding for global variable ‘y’ .reactive_transcExpr_plots: no visible binding for global variable ‘x’ .reactive_transcExpr_plots: no visible binding for global variable ‘y’ .run_reactive_tf_enrich: no visible binding for '<<-' assignment to ‘bg_process’ .server_enrich_bg : <anonymous>: no visible binding for global variable ‘bg_process’ .server_enrich_bgTF: no visible binding for '<<-' assignment to ‘bg_process’ .server_enrich_bgTF : <anonymous>: no visible binding for global variable ‘bg_process’ .shiny_preprocess: no visible binding for global variable ‘cov’ plot_tf_distribution: no visible binding for global variable ‘Freq’ Undefined global functions or variables: Freq bg_process chr_cov cnv cnv_met coef combn contrasts.fit cov met mirna_cnv omics pval significance x y Consider adding importFrom("stats", "coef", "cov") importFrom("utils", "combn") to your NAMESPACE file. * checking Rd files ... OK * checking Rd metadata ... OK * checking Rd cross-references ... NOTE Found the following Rd file(s) with Rd \link{} targets missing package anchors: mmultiassay_ov.Rd: MultiAssayExperiment-class Please provide package anchors for all Rd \link{} targets not in the package itself and the base packages. * checking for missing documentation entries ... OK * checking for code/documentation mismatches ... OK * checking Rd \usage sections ... OK * checking Rd contents ... OK * checking for unstated dependencies in examples ... OK * checking contents of ‘data’ directory ... OK * checking data for non-ASCII characters ... OK * checking data for ASCII and uncompressed saves ... OK * checking R/sysdata.rda ... OK * checking files in ‘vignettes’ ... OK * checking examples ... ERROR Running examples in ‘gINTomics-Ex.R’ failed The error most likely occurred in: > base::assign(".ptime", proc.time(), pos = "CheckExEnv") > ### Name: plot_volcano > ### Title: plotting volcano > ### Aliases: plot_volcano > > ### ** Examples > > # Example usage: > library(MultiAssayExperiment) Loading required package: SummarizedExperiment Loading required package: MatrixGenerics Loading required package: matrixStats Attaching package: ‘MatrixGenerics’ The following objects are masked from ‘package:matrixStats’: colAlls, colAnyNAs, colAnys, colAvgsPerRowSet, colCollapse, colCounts, colCummaxs, colCummins, colCumprods, colCumsums, colDiffs, colIQRDiffs, colIQRs, colLogSumExps, colMadDiffs, colMads, colMaxs, colMeans2, colMedians, colMins, colOrderStats, colProds, colQuantiles, colRanges, colRanks, colSdDiffs, colSds, colSums2, colTabulates, colVarDiffs, colVars, colWeightedMads, colWeightedMeans, colWeightedMedians, colWeightedSds, colWeightedVars, rowAlls, rowAnyNAs, rowAnys, rowAvgsPerColSet, rowCollapse, rowCounts, rowCummaxs, rowCummins, rowCumprods, rowCumsums, rowDiffs, rowIQRDiffs, rowIQRs, rowLogSumExps, rowMadDiffs, rowMads, rowMaxs, rowMeans2, rowMedians, rowMins, rowOrderStats, rowProds, rowQuantiles, rowRanges, rowRanks, rowSdDiffs, rowSds, rowSums2, rowTabulates, rowVarDiffs, rowVars, rowWeightedMads, rowWeightedMeans, rowWeightedMedians, rowWeightedSds, rowWeightedVars Loading required package: GenomicRanges Loading required package: stats4 Loading required package: BiocGenerics Loading required package: generics Attaching package: ‘generics’ The following objects are masked from ‘package:base’: as.difftime, as.factor, as.ordered, intersect, is.element, setdiff, setequal, union Attaching package: ‘BiocGenerics’ The following objects are masked from ‘package:stats’: IQR, mad, sd, var, xtabs The following objects are masked from ‘package:base’: Filter, Find, Map, Position, Reduce, anyDuplicated, aperm, append, as.data.frame, basename, cbind, colnames, dirname, do.call, duplicated, eval, evalq, get, grep, grepl, is.unsorted, lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin, pmin.int, rank, rbind, rownames, sapply, saveRDS, table, tapply, unique, unsplit, which.max, which.min Loading required package: S4Vectors Attaching package: ‘S4Vectors’ The following object is masked from ‘package:utils’: findMatches The following objects are masked from ‘package:base’: I, expand.grid, unname Loading required package: IRanges Loading required package: Seqinfo Loading required package: Biobase Welcome to Bioconductor Vignettes contain introductory material; view with 'browseVignettes()'. To cite Bioconductor, see 'citation("Biobase")', and for packages 'citation("pkgname")'. Attaching package: ‘Biobase’ The following object is masked from ‘package:MatrixGenerics’: rowMedians The following objects are masked from ‘package:matrixStats’: anyMissing, rowMedians > data("mmultiassay_ov") > tmp <- lapply(experiments(mmultiassay_ov), function(x) x[1:20,]) > mmultiassay_ov <- MultiAssayExperiment(experiments = tmp) > multiomics_integration <- run_multiomics(data = mmultiassay_ov) --------------Running gene genomic integration-------------- Generating interactions ---------------Running miRNA CNV integration---------------- Generating interactions removing response variables with zero standard deviation Warning in .data_check(response_var = response_var, covariates = covariates, : No genes left in common between response_var and interactions -------------------Running TF integration------------------- Warning in import_tf_target_interactions(organism = org[species]) : 'import_tf_target_interactions' is deprecated. Use 'tf_target' instead. See help("Deprecated") [2025-09-21 21:33:59] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-09-21 21:33:59] [TRACE] [OmnipathR] Arguments for OmniPath query: [organisms=9606,query_type=interactions,datasets=tf_target] [2025-09-21 21:33:59] [INFO] [OmnipathR] Loading database `Ensembl and OMA organism names`. [2025-09-21 21:33:59] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:33:59] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:33:59] [INFO] [OmnipathR] Looking up in cache `https://www.ensembl.org/info/about/species.html`: key=7332486db7400730697234bad76ca0c8e4d00799, no version available. [2025-09-21 21:33:59] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:33:59] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:33:59] [INFO] [OmnipathR] Created new version for cache record 7332486db7400730697234bad76ca0c8e4d00799: version 1. [2025-09-21 21:33:59] [TRACE] [OmnipathR] Cache file path: /Users/biocbuild/Library/Caches/OmnipathR/7332486db7400730697234bad76ca0c8e4d00799-1.html [2025-09-21 21:33:59] [INFO] [OmnipathR] Retrieving URL: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:33:59] [TRACE] [OmnipathR] Downloading by `httr2` in `download_base`. [2025-09-21 21:33:59] [TRACE] [OmnipathR] Attempt 1/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:33:59] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:33:59] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:33:59] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:34:00] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:34:00] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:35:01] [WARN] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 1/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:35:06] [TRACE] [OmnipathR] Attempt 2/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:35:06] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:35:06] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:35:06] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:35:06] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:35:06] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:36:36] [WARN] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 2/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:36:42] [TRACE] [OmnipathR] Attempt 3/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:36:42] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:36:42] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:36:42] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:36:42] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:36:42] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:38:12] [ERROR] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 3/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:38:12] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 21:38:12] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 21:38:12] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 21:38:12] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 21:38:12] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 21:38:13] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=en; collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 21:38:13] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 21:38:14] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); ape 5.8-1(2024-12-16); aplot 0.2.9(2025-09-12); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocFileCache 2.99.6(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); biomaRt 2.65.14(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); callr 3.7.6(2024-03-25); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); clusterProfiler 4.17.0(2025-09-21); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); cowplot 1.2.0(2025-07-07); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); data.table 1.17.8(2025-07-10); DBI 1.2.3(2024-06-02); dbplyr 2.5.1(2025-09-10); DelayedArray 0.35.3(2025-09-21); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); DOSE 4.3.0(2025-09-21); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); edgeR 4.7.4(2025-09-21); enrichplot 1.29.2(2025-09-21); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fastmatch 1.1-6(2024-12-23); fgsea 1.35.6(2025-09-21); filelock 1.0.3(2023-12-11); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggforce 0.5.0(2025-06-18); ggfun 0.2.0(2025-07-15); ggiraph 0.9.1(2025-09-16); ggplot2 4.0.0(2025-09-11); ggplotify 0.1.3(2025-09-20); ggraph 2.2.2(2025-08-24); ggrepel 0.9.6(2024-09-07); ggridges 0.5.7(2025-08-27); ggtangle 0.0.7(2025-06-30); ggtree 3.99.0(2025-09-21); ggvenn 0.1.10(2023-03-31); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); GO.db 3.21.0(2025-09-10); GOSemSim 2.35.1(2025-09-21); graph 1.87.0(2025-09-21); graphite 1.55.0(2025-09-21); graphlayouts 1.2.2(2025-01-23); gridExtra 2.3(2017-09-09); gridGraphics 0.5-1(2020-12-13); gson 0.1.0(2023-03-07); gtable 0.3.6(2024-10-25); gtools 3.9.5(2023-11-20); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); labeling 0.4.3(2023-08-29); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lazyeval 0.2.2(2019-03-15); lifecycle 1.0.4(2023-11-07); limma 3.65.4(2025-09-21); locfit 1.5-9.12(2025-03-05); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); nlme 3.1-168(2025-03-31); OmnipathR 3.17.4(2025-09-21); org.Hs.eg.db 3.21.0(2025-09-10); org.Mm.eg.db 3.21.0(2025-09-10); patchwork 1.3.2(2025-08-25); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); plotly 4.11.0(2025-06-19); plyr 1.8.9(2023-10-02); png 0.1-8(2022-11-29); polyclip 1.10-7(2024-07-23); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); qvalue 2.41.0(2025-09-21); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); randomForest 4.7-1.2(2024-09-22); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); reactome.db 1.92.0(2025-09-10); ReactomePA 1.53.0(2025-09-21); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); reshape2 1.4.4(2020-04-09); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); shiny.gosling 1.5.0(2025-09-21); shinydashboard 0.7.3(2025-04-21); shinyjs 2.1.0(2021-12-23); SparseArray 1.9.1(2025-09-21); statmod 1.5.0(2023-01-06); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidygraph 1.3.1(2024-01-30); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); tidytree 0.4.6(2023-12-12); timechange 0.3.0(2024-01-18); treeio 1.33.0(2025-09-21); tweenr 2.0.3(2024-02-26); TxDb.Hsapiens.UCSC.hg38.knownGene 3.21.0(2025-09-10); TxDb.Mmusculus.UCSC.mm10.knownGene 3.10.0(2025-09-10); tzdb 0.5.0(2025-03-15); uuid 1.2-1(2024-07-29); vctrs 0.6.5(2023-12-01); viridis 0.6.5(2024-01-29); viridisLite 0.4.2(2023-05-02); visNetwork 2.1.4(2025-09-04); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); yulab.utils 0.2.1(2025-08-19); zip 2.3.3(2025-05-13) [2025-09-21 21:38:14] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE Error in `map_int()`: ℹ In index: 1. ℹ With name: hsa. Caused by error in `map_int()`: ℹ In index: 1. Caused by error in `req_perform()`: ! HTTP 504 Gateway Timeout. Backtrace: ▆ 1. ├─gINTomics::run_multiomics(data = mmultiassay_ov) 2. │ └─gINTomics::run_tf_integration(...) 3. │ └─gINTomics:::.def_tf_integration(...) 4. │ └─gINTomics:::.download_tf(genes = colnames(expression), species = species) 5. │ └─OmnipathR::import_tf_target_interactions(organism = org[species]) 6. │ └─OmnipathR::tf_target(...) 7. │ ├─rlang::exec(omnipath_query, !!!args) 8. │ └─OmnipathR (local) `<fn>`(organisms = `<dbl>`, query_type = "interactions", datasets = "tf_target") 9. │ └─environment() %>% as.list %>% c(list(...)) %>% ... 10. ├─OmnipathR:::omnipath_check_param(.) 11. │ └─param$organisms %<>% map_int(ncbi_taxid) 12. ├─purrr::map_int(., ncbi_taxid) 13. │ └─purrr:::map_("integer", .x, .f, ..., .progress = .progress) 14. │ ├─purrr:::with_indexed_errors(...) 15. │ │ └─base::withCallingHandlers(...) 16. │ ├─purrr:::call_with_cleanup(...) 17. │ └─OmnipathR (local) .f(.x[[i]], ...) 18. │ └─name %>% map_int(taxon_name, "ncbi") %>% as.integer 19. ├─purrr::map_int(., taxon_name, "ncbi") 20. │ └─purrr:::map_("integer", .x, .f, ..., .progress = .progress) 21. │ ├─purrr:::with_indexed_errors(...) 22. │ │ └─base::withCallingHandlers(...) 23. │ ├─purrr:::call_with_cleanup(...) 24. │ └─OmnipathR (local) .f(.x[[i]], ...) 25. │ ├─... %>% if_null_len0(NA) 26. │ └─OmnipathR::get_db("organisms") 27. │ └─OmnipathR::load_db(key, param = param) 28. │ ├─rlang::exec(loader, !!!param) 29. │ └─OmnipathR (local) `<fn>`() 30. │ ├─... %>% ... 31. │ └─OmnipathR::ensembl_organisms() 32. │ ├─... %>% ... 33. │ └─OmnipathR::ensembl_organisms_raw() 34. │ └─... %>% html_table() 35. ├─OmnipathR:::if_null_len0(., NA) 36. │ └─value1 %>% is_empty_2 %>% if (value2) value1 37. ├─OmnipathR:::is_empty_2(.) 38. │ └─value %>% ... 39. ├─dplyr::pull(., name_type) 40. ├─dplyr::filter(...) 41. ├─dplyr::mutate(...) 42. ├─dplyr::full_join(...) 43. ├─dplyr::full_join(...) 44. ├─dplyr::rename(., common_name_ensembl = common_name) 45. ├─dplyr::mutate(...) 46. ├─dplyr::select(...) 47. ├─rvest::html_table(.) 48. ├─rvest::html_element(., "table") 49. ├─xml2::read_html(.) 50. ├─OmnipathR:::download_to_cache(., http_headers = user_agent()) 51. │ └─OmnipathR:::download_base(...) 52. │ ├─base::tryCatch(exec(fun, url, !!!args), error = identity) 53. │ │ └─base (local) tryCatchList(expr, classes, parentenv, handlers) 54. │ │ └─base (local) tryCatchOne(expr, names, parentenv, handlers[[1L]]) 55. │ │ └─base (local) doTryCatch(return(expr), name, parentenv, handler) 56. │ ├─rlang::exec(fun, url, !!!args) 57. │ └─OmnipathR (local) `<fn>`("https://www.ensembl.org/info/about/species.html") 58. │ └─req %>% omnipath_httr2_perform(path = path) 59. ├─OmnipathR:::omnipath_httr2_perform(., path = path) 60. │ └─req %>% req_perform(path = path) 61. └─httr2::req_perform(., path = path) 62. └─httr2:::handle_resp(req, resp, error_call = error_call) 63. └─httr2:::resp_failure_cnd(req, resp, error_call = error_call) 64. ├─rlang::catch_cnd(...) 65. │ ├─rlang::eval_bare(...) 66. │ ├─base::tryCatch(...) 67. │ │ └─base (local) tryCatchList(expr, classes, parentenv, handlers) 68. │ │ └─base (local) tryCatchOne(expr, names, parentenv, handlers[[1L]]) 69. │ │ └─base (local) doTryCatch(return(expr), name, parentenv, handler) 70. │ └─base::force(expr) 71. └─rlang::abort(...) Execution halted Examples with CPU (user + system) or elapsed time > 5s user system elapsed extract_model_res 15.380 1.538 20.248 plot_ridge 12.064 1.418 16.194 * checking for unstated dependencies in ‘tests’ ... OK * checking tests ... Running ‘testthat.R’ ERROR Running the tests in ‘tests/testthat.R’ failed. Last 13 lines of output: names(tested)[1] (`actual`) not equal to "data" (`expected`). `actual` is NULL `expected` is a character vector ('data') ── Failure ('test-outputs_shiny.R:184:3'): .build_histo works ────────────────── `tested` has type 'object', not 'list'. ── Failure ('test-outputs_shiny.R:186:3'): .build_histo works ────────────────── names(tested)[1] (`actual`) not equal to "data" (`expected`). `actual` is NULL `expected` is a character vector ('data') [ FAIL 9 | WARN 5 | SKIP 0 | PASS 193 ] Error: Test failures Execution halted * checking for unstated dependencies in vignettes ... OK * checking package vignettes ... OK * checking running R code from vignettes ... SKIPPED * checking re-building of vignette outputs ... SKIPPED * checking PDF version of manual ... OK * DONE Status: 2 ERRORs, 2 NOTEs See ‘/Users/biocbuild/bbs-3.22-bioc/meat/gINTomics.Rcheck/00check.log’ for details.
gINTomics.Rcheck/00install.out
############################################################################## ############################################################################## ### ### Running command: ### ### /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL gINTomics ### ############################################################################## ############################################################################## * installing to library ‘/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library’ * installing *source* package ‘gINTomics’ ... ** this is package ‘gINTomics’ version ‘1.5.0’ ** using staged installation ** R [2025-09-21 15:46:29] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 15:46:29] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:46:29] [INFO] [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:46:29] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 15:46:29] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 15:46:29] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 15:46:29] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 15:46:29] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 15:46:31] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 15:46:31] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 15:46:32] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); DelayedArray 0.35.3(2025-09-21); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggplot2 4.0.0(2025-09-11); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); gtable 0.3.6(2024-10-25); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); OmnipathR 3.17.4(2025-09-21); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); SparseArray 1.9.1(2025-09-21); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); viridisLite 0.4.2(2023-05-02); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13) [2025-09-21 15:46:32] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE [2025-09-21 15:46:32] [TRACE] [OmnipathR] Running on a build server, wiping cache. [2025-09-21 15:46:32] [TRACE] [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:46:32] [TRACE] [OmnipathR] Contains 1 files. [2025-09-21 15:46:32] [TRACE] [OmnipathR] Cache is locked: FALSE. [2025-09-21 15:46:32] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 15:46:32] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:46:32] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:46:32] [TRACE] [OmnipathR] Pandoc version: `2.7.3`. [2025-09-21 15:46:32] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8). [2025-09-21 15:46:32] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:46:32] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8). [2025-09-21 15:46:32] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:46:32] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8). [2025-09-21 15:46:32] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:46:32] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8). [2025-09-21 15:46:32] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:46:32] [TRACE] [OmnipathR] Cache locked: FALSE ** data ** inst ** byte-compile and prepare package for lazy loading [2025-09-21 15:46:57] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 15:46:57] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:46:57] [INFO] [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:46:57] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 15:46:57] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 15:46:57] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 15:46:57] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 15:46:57] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 15:46:58] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 15:46:58] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 15:47:00] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); DelayedArray 0.35.3(2025-09-21); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggplot2 4.0.0(2025-09-11); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); gtable 0.3.6(2024-10-25); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); OmnipathR 3.17.4(2025-09-21); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); SparseArray 1.9.1(2025-09-21); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); viridisLite 0.4.2(2023-05-02); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13) [2025-09-21 15:47:00] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE [2025-09-21 15:47:00] [TRACE] [OmnipathR] Running on a build server, wiping cache. [2025-09-21 15:47:00] [TRACE] [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:47:00] [TRACE] [OmnipathR] Contains 1 files. [2025-09-21 15:47:00] [TRACE] [OmnipathR] Cache is locked: FALSE. [2025-09-21 15:47:00] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 15:47:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:00] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:47:00] [TRACE] [OmnipathR] Pandoc version: `2.7.3`. [2025-09-21 15:47:00] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8). [2025-09-21 15:47:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:00] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8). [2025-09-21 15:47:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:00] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8). [2025-09-21 15:47:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:00] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8). [2025-09-21 15:47:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:00] [TRACE] [OmnipathR] Cache locked: FALSE ** help *** installing help indices *** copying figures ** building package indices ** installing vignettes ** testing if installed package can be loaded from temporary location [2025-09-21 15:47:36] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 15:47:36] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:36] [INFO] [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:47:36] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 15:47:36] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 15:47:36] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 15:47:36] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 15:47:36] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 15:47:37] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 15:47:38] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 15:47:39] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); DelayedArray 0.35.3(2025-09-21); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggplot2 4.0.0(2025-09-11); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); gtable 0.3.6(2024-10-25); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); OmnipathR 3.17.4(2025-09-21); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); SparseArray 1.9.1(2025-09-21); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); viridisLite 0.4.2(2023-05-02); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13) [2025-09-21 15:47:39] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE [2025-09-21 15:47:39] [TRACE] [OmnipathR] Running on a build server, wiping cache. [2025-09-21 15:47:39] [TRACE] [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:47:39] [TRACE] [OmnipathR] Contains 1 files. [2025-09-21 15:47:39] [TRACE] [OmnipathR] Cache is locked: FALSE. [2025-09-21 15:47:39] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 15:47:39] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:39] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:47:39] [TRACE] [OmnipathR] Pandoc version: `2.7.3`. [2025-09-21 15:47:39] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8). [2025-09-21 15:47:39] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:39] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8). [2025-09-21 15:47:39] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:39] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8). [2025-09-21 15:47:39] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:39] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8). [2025-09-21 15:47:39] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:47:39] [TRACE] [OmnipathR] Cache locked: FALSE ** testing if installed package can be loaded from final location [2025-09-21 15:48:03] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 15:48:03] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:48:03] [INFO] [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:48:03] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 15:48:03] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 15:48:03] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 15:48:03] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 15:48:03] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 15:48:04] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 15:48:05] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 15:48:06] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); DelayedArray 0.35.3(2025-09-21); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggplot2 4.0.0(2025-09-11); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); gtable 0.3.6(2024-10-25); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); OmnipathR 3.17.4(2025-09-21); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); SparseArray 1.9.1(2025-09-21); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); viridisLite 0.4.2(2023-05-02); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13) [2025-09-21 15:48:06] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE [2025-09-21 15:48:06] [TRACE] [OmnipathR] Running on a build server, wiping cache. [2025-09-21 15:48:06] [TRACE] [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:48:06] [TRACE] [OmnipathR] Contains 1 files. [2025-09-21 15:48:06] [TRACE] [OmnipathR] Cache is locked: FALSE. [2025-09-21 15:48:06] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 15:48:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:48:06] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 15:48:06] [TRACE] [OmnipathR] Pandoc version: `2.7.3`. [2025-09-21 15:48:06] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8). [2025-09-21 15:48:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:48:06] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8). [2025-09-21 15:48:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:48:06] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8). [2025-09-21 15:48:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:48:06] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8). [2025-09-21 15:48:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 15:48:06] [TRACE] [OmnipathR] Cache locked: FALSE ** testing if installed package keeps a record of temporary installation path * DONE (gINTomics)
gINTomics.Rcheck/tests/testthat.Rout.fail
R version 4.5.1 Patched (2025-09-10 r88807) -- "Great Square Root" Copyright (C) 2025 The R Foundation for Statistical Computing Platform: x86_64-apple-darwin20 R is free software and comes with ABSOLUTELY NO WARRANTY. You are welcome to redistribute it under certain conditions. Type 'license()' or 'licence()' for distribution details. R is a collaborative project with many contributors. Type 'contributors()' for more information and 'citation()' on how to cite R or R packages in publications. Type 'demo()' for some demos, 'help()' for on-line help, or 'help.start()' for an HTML browser interface to help. Type 'q()' to quit R. > library(testthat) > library(gINTomics) [2025-09-21 21:38:33] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:38:33] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:38:33] [INFO] [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 21:38:33] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 21:38:33] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 21:38:33] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 21:38:33] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 21:38:33] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 21:38:34] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=C; collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 21:38:35] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 21:38:35] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); brio 1.1.5(2024-04-24); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); DBI 1.2.3(2024-06-02); DelayedArray 0.35.3(2025-09-21); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggplot2 4.0.0(2025-09-11); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); gtable 0.3.6(2024-10-25); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lifecycle 1.0.4(2023-11-07); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); OmnipathR 3.17.4(2025-09-21); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); SparseArray 1.9.1(2025-09-21); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); testthat 3.2.3(2025-01-13); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); viridisLite 0.4.2(2023-05-02); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); zip 2.3.3(2025-05-13) [2025-09-21 21:38:35] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE [2025-09-21 21:38:35] [TRACE] [OmnipathR] Running on a build server, wiping cache. [2025-09-21 21:38:35] [TRACE] [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 21:38:35] [TRACE] [OmnipathR] Contains 2 files. [2025-09-21 21:38:35] [TRACE] [OmnipathR] Cache is locked: FALSE. [2025-09-21 21:38:35] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:38:35] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:38:35] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`. [2025-09-21 21:38:35] [TRACE] [OmnipathR] Pandoc version: `2.7.3`. [2025-09-21 21:38:35] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8). [2025-09-21 21:38:35] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:38:35] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8). [2025-09-21 21:38:35] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:38:35] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8). [2025-09-21 21:38:35] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:38:35] [TRACE] [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8). [2025-09-21 21:38:35] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:38:35] [TRACE] [OmnipathR] Cache locked: FALSE > > test_check("gINTomics") [2025-09-21 21:38:42] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-09-21 21:38:42] [TRACE] [OmnipathR] Arguments for OmniPath query: [organisms=9606,query_type=interactions,datasets=mirnatarget] [2025-09-21 21:38:42] [INFO] [OmnipathR] Loading database `Ensembl and OMA organism names`. [2025-09-21 21:38:42] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:38:42] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:38:42] [INFO] [OmnipathR] Looking up in cache `https://www.ensembl.org/info/about/species.html`: key=7332486db7400730697234bad76ca0c8e4d00799, no version available. [2025-09-21 21:38:42] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:38:42] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:38:42] [INFO] [OmnipathR] Created new version for cache record 7332486db7400730697234bad76ca0c8e4d00799: version 1. [2025-09-21 21:38:42] [TRACE] [OmnipathR] Cache file path: /Users/biocbuild/Library/Caches/OmnipathR/7332486db7400730697234bad76ca0c8e4d00799-1.html [2025-09-21 21:38:42] [INFO] [OmnipathR] Retrieving URL: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:38:42] [TRACE] [OmnipathR] Downloading by `httr2` in `download_base`. [2025-09-21 21:38:42] [TRACE] [OmnipathR] Attempt 1/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:38:42] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:38:42] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:38:42] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:38:42] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:38:42] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:40:13] [WARN] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 1/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:40:18] [TRACE] [OmnipathR] Attempt 2/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:40:18] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:40:18] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:40:18] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:40:18] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:40:18] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:41:49] [WARN] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 2/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:41:54] [TRACE] [OmnipathR] Attempt 3/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:41:54] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:41:54] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:41:54] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:41:54] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:41:54] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:43:24] [ERROR] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 3/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:43:24] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 21:43:24] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 21:43:24] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 21:43:24] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 21:43:24] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 21:43:26] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=C; collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 21:43:26] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 21:43:26] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); ape 5.8-1(2024-12-16); aplot 0.2.9(2025-09-12); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocFileCache 2.99.6(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); biomaRt 2.65.14(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); brio 1.1.5(2024-04-24); cachem 1.1.0(2024-05-16); callr 3.7.6(2024-03-25); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); clusterProfiler 4.17.0(2025-09-21); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); cowplot 1.2.0(2025-07-07); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); data.table 1.17.8(2025-07-10); DBI 1.2.3(2024-06-02); dbplyr 2.5.1(2025-09-10); DelayedArray 0.35.3(2025-09-21); desc 1.4.3(2023-12-10); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); DOSE 4.3.0(2025-09-21); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); edgeR 4.7.4(2025-09-21); enrichplot 1.29.2(2025-09-21); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fastmatch 1.1-6(2024-12-23); fgsea 1.35.6(2025-09-21); filelock 1.0.3(2023-12-11); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggforce 0.5.0(2025-06-18); ggfun 0.2.0(2025-07-15); ggiraph 0.9.1(2025-09-16); ggplot2 4.0.0(2025-09-11); ggplotify 0.1.3(2025-09-20); ggraph 2.2.2(2025-08-24); ggrepel 0.9.6(2024-09-07); ggridges 0.5.7(2025-08-27); ggtangle 0.0.7(2025-06-30); ggtree 3.99.0(2025-09-21); ggvenn 0.1.10(2023-03-31); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); GO.db 3.21.0(2025-09-10); GOSemSim 2.35.1(2025-09-21); graph 1.87.0(2025-09-21); graphite 1.55.0(2025-09-21); graphlayouts 1.2.2(2025-01-23); gridExtra 2.3(2017-09-09); gridGraphics 0.5-1(2020-12-13); gson 0.1.0(2023-03-07); gtable 0.3.6(2024-10-25); gtools 3.9.5(2023-11-20); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lazyeval 0.2.2(2019-03-15); lifecycle 1.0.4(2023-11-07); limma 3.65.4(2025-09-21); locfit 1.5-9.12(2025-03-05); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); nlme 3.1-168(2025-03-31); OmnipathR 3.17.4(2025-09-21); org.Hs.eg.db 3.21.0(2025-09-10); org.Mm.eg.db 3.21.0(2025-09-10); patchwork 1.3.2(2025-08-25); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); plotly 4.11.0(2025-06-19); plyr 1.8.9(2023-10-02); png 0.1-8(2022-11-29); polyclip 1.10-7(2024-07-23); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); qvalue 2.41.0(2025-09-21); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); randomForest 4.7-1.2(2024-09-22); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); reactome.db 1.92.0(2025-09-10); ReactomePA 1.53.0(2025-09-21); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); reshape2 1.4.4(2020-04-09); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); shiny.gosling 1.5.0(2025-09-21); shinydashboard 0.7.3(2025-04-21); shinyjs 2.1.0(2021-12-23); SparseArray 1.9.1(2025-09-21); statmod 1.5.0(2023-01-06); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); testthat 3.2.3(2025-01-13); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidygraph 1.3.1(2024-01-30); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); tidytree 0.4.6(2023-12-12); timechange 0.3.0(2024-01-18); treeio 1.33.0(2025-09-21); tweenr 2.0.3(2024-02-26); TxDb.Hsapiens.UCSC.hg38.knownGene 3.21.0(2025-09-10); TxDb.Mmusculus.UCSC.mm10.knownGene 3.10.0(2025-09-10); tzdb 0.5.0(2025-03-15); uuid 1.2-1(2024-07-29); vctrs 0.6.5(2023-12-01); viridis 0.6.5(2024-01-29); viridisLite 0.4.2(2023-05-02); visNetwork 2.1.4(2025-09-04); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); yulab.utils 0.2.1(2025-08-19); zip 2.3.3(2025-05-13) [2025-09-21 21:43:26] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE [2025-09-21 21:43:28] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-09-21 21:43:28] [TRACE] [OmnipathR] Arguments for OmniPath query: [resources=TransmiR,organisms=9606,query_type=interactions,datasets=tf_mirna] [2025-09-21 21:43:28] [INFO] [OmnipathR] Loading database `Ensembl and OMA organism names`. [2025-09-21 21:43:28] [INFO] [OmnipathR] Looking up in cache `https://www.ensembl.org/info/about/species.html`: key=7332486db7400730697234bad76ca0c8e4d00799, no version available. [2025-09-21 21:43:28] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:43:28] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:43:28] [INFO] [OmnipathR] Created new version for cache record 7332486db7400730697234bad76ca0c8e4d00799: version 2. [2025-09-21 21:43:28] [TRACE] [OmnipathR] Cache file path: /Users/biocbuild/Library/Caches/OmnipathR/7332486db7400730697234bad76ca0c8e4d00799-2.html [2025-09-21 21:43:28] [INFO] [OmnipathR] Retrieving URL: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:43:28] [TRACE] [OmnipathR] Downloading by `httr2` in `download_base`. [2025-09-21 21:43:28] [TRACE] [OmnipathR] Attempt 1/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:43:28] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:43:28] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:43:28] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:43:28] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:43:28] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:44:59] [WARN] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 1/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:45:04] [TRACE] [OmnipathR] Attempt 2/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:45:04] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:45:04] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:45:04] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:45:04] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:45:04] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:46:34] [WARN] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 2/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:46:39] [TRACE] [OmnipathR] Attempt 3/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:46:39] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:46:39] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:46:39] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:46:39] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:46:39] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:48:10] [ERROR] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 3/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:48:10] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 21:48:10] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 21:48:10] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 21:48:10] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 21:48:10] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 21:48:11] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=C; collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 21:48:11] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 21:48:12] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); ape 5.8-1(2024-12-16); aplot 0.2.9(2025-09-12); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocFileCache 2.99.6(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); biomaRt 2.65.14(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); brio 1.1.5(2024-04-24); cachem 1.1.0(2024-05-16); callr 3.7.6(2024-03-25); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); clusterProfiler 4.17.0(2025-09-21); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); cowplot 1.2.0(2025-07-07); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); data.table 1.17.8(2025-07-10); DBI 1.2.3(2024-06-02); dbplyr 2.5.1(2025-09-10); DelayedArray 0.35.3(2025-09-21); desc 1.4.3(2023-12-10); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); DOSE 4.3.0(2025-09-21); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); edgeR 4.7.4(2025-09-21); enrichplot 1.29.2(2025-09-21); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fastmatch 1.1-6(2024-12-23); fgsea 1.35.6(2025-09-21); filelock 1.0.3(2023-12-11); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggforce 0.5.0(2025-06-18); ggfun 0.2.0(2025-07-15); ggiraph 0.9.1(2025-09-16); ggplot2 4.0.0(2025-09-11); ggplotify 0.1.3(2025-09-20); ggraph 2.2.2(2025-08-24); ggrepel 0.9.6(2024-09-07); ggridges 0.5.7(2025-08-27); ggtangle 0.0.7(2025-06-30); ggtree 3.99.0(2025-09-21); ggvenn 0.1.10(2023-03-31); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); GO.db 3.21.0(2025-09-10); GOSemSim 2.35.1(2025-09-21); graph 1.87.0(2025-09-21); graphite 1.55.0(2025-09-21); graphlayouts 1.2.2(2025-01-23); gridExtra 2.3(2017-09-09); gridGraphics 0.5-1(2020-12-13); gson 0.1.0(2023-03-07); gtable 0.3.6(2024-10-25); gtools 3.9.5(2023-11-20); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lazyeval 0.2.2(2019-03-15); lifecycle 1.0.4(2023-11-07); limma 3.65.4(2025-09-21); locfit 1.5-9.12(2025-03-05); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); nlme 3.1-168(2025-03-31); OmnipathR 3.17.4(2025-09-21); org.Hs.eg.db 3.21.0(2025-09-10); org.Mm.eg.db 3.21.0(2025-09-10); patchwork 1.3.2(2025-08-25); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); plotly 4.11.0(2025-06-19); plyr 1.8.9(2023-10-02); png 0.1-8(2022-11-29); polyclip 1.10-7(2024-07-23); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); qvalue 2.41.0(2025-09-21); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); randomForest 4.7-1.2(2024-09-22); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); reactome.db 1.92.0(2025-09-10); ReactomePA 1.53.0(2025-09-21); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); reshape2 1.4.4(2020-04-09); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); shiny.gosling 1.5.0(2025-09-21); shinydashboard 0.7.3(2025-04-21); shinyjs 2.1.0(2021-12-23); SparseArray 1.9.1(2025-09-21); statmod 1.5.0(2023-01-06); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); testthat 3.2.3(2025-01-13); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidygraph 1.3.1(2024-01-30); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); tidytree 0.4.6(2023-12-12); timechange 0.3.0(2024-01-18); treeio 1.33.0(2025-09-21); tweenr 2.0.3(2024-02-26); TxDb.Hsapiens.UCSC.hg38.knownGene 3.21.0(2025-09-10); TxDb.Mmusculus.UCSC.mm10.knownGene 3.10.0(2025-09-10); tzdb 0.5.0(2025-03-15); uuid 1.2-1(2024-07-29); vctrs 0.6.5(2023-12-01); viridis 0.6.5(2024-01-29); viridisLite 0.4.2(2023-05-02); visNetwork 2.1.4(2025-09-04); waldo 0.6.2(2025-07-11); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); yulab.utils 0.2.1(2025-08-19); zip 2.3.3(2025-05-13) [2025-09-21 21:48:12] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE [2025-09-21 21:48:13] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-09-21 21:48:13] [TRACE] [OmnipathR] Arguments for OmniPath query: [organisms=9606,query_type=interactions,datasets=tf_target] [2025-09-21 21:48:13] [INFO] [OmnipathR] Loading database `Ensembl and OMA organism names`. [2025-09-21 21:48:13] [INFO] [OmnipathR] Looking up in cache `https://www.ensembl.org/info/about/species.html`: key=7332486db7400730697234bad76ca0c8e4d00799, no version available. [2025-09-21 21:48:13] [TRACE] [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8). [2025-09-21 21:48:13] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-09-21 21:48:13] [INFO] [OmnipathR] Created new version for cache record 7332486db7400730697234bad76ca0c8e4d00799: version 3. [2025-09-21 21:48:13] [TRACE] [OmnipathR] Cache file path: /Users/biocbuild/Library/Caches/OmnipathR/7332486db7400730697234bad76ca0c8e4d00799-3.html [2025-09-21 21:48:13] [INFO] [OmnipathR] Retrieving URL: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:48:13] [TRACE] [OmnipathR] Downloading by `httr2` in `download_base`. [2025-09-21 21:48:13] [TRACE] [OmnipathR] Attempt 1/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:48:13] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:48:13] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:48:13] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:48:13] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:48:13] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:49:44] [WARN] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 1/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:49:49] [TRACE] [OmnipathR] Attempt 2/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:49:49] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:49:49] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:49:49] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:49:49] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:49:49] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:51:20] [WARN] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 2/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:51:25] [TRACE] [OmnipathR] Attempt 3/3: `https://www.ensembl.org/info/about/species.html` [2025-09-21 21:51:25] [TRACE] [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`. [2025-09-21 21:51:25] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:51:25] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2] [2025-09-21 21:51:25] [TRACE] [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0] [2025-09-21 21:51:25] [TRACE] [OmnipathR] Sending HTTP request. [2025-09-21 21:52:56] [ERROR] [OmnipathR] Failed to download `https://www.ensembl.org/info/about/species.html` (attempt 3/3); error: HTTP 504 Gateway Timeout. [2025-09-21 21:52:56] [INFO] [OmnipathR] Package `OmnipathR` packaged: NA [2025-09-21 21:52:56] [INFO] [OmnipathR] Package `OmnipathR` date/publication: 2025-09-21 [2025-09-21 21:52:56] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.1; ; 2025-09-21 19:11:42 UTC; unix [2025-09-21 21:52:56] [INFO] [OmnipathR] Package `OmnipathR` version: 3.17.4 [2025-09-21 21:52:56] [INFO] [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.22 [2025-09-21 21:52:57] [INFO] [OmnipathR] Session info: [version=R version 4.5.1 Patched (2025-09-10 r88807); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=C; collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-09-21; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=1.4.553 @ /usr/local/bin/quarto] [2025-09-21 21:52:57] [INFO] [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.1] [2025-09-21 21:52:57] [INFO] [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); AnnotationDbi 1.71.1(2025-09-21); ape 5.8-1(2024-12-16); aplot 0.2.9(2025-09-12); backports 1.5.0(2024-05-23); Biobase 2.69.1(2025-09-21); BiocBaseUtils 1.11.2(2025-09-21); BiocFileCache 2.99.6(2025-09-21); BiocGenerics 0.55.1(2025-09-21); BiocIO 1.19.0(2025-09-21); BiocParallel 1.43.4(2025-09-21); biomaRt 2.65.14(2025-09-21); Biostrings 2.77.2(2025-09-21); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); bitops 1.0-9(2024-10-03); blob 1.2.4(2023-03-17); brio 1.1.5(2024-04-24); cachem 1.1.0(2024-05-16); callr 3.7.6(2024-03-25); cellranger 1.1.0(2016-07-27); checkmate 2.3.3(2025-08-18); chromote 0.5.1(2025-04-24); circlize 0.4.16(2024-02-20); cli 3.6.5(2025-04-23); clisymbols 1.2.0(2017-05-21); clue 0.3-66(2024-11-13); cluster 2.1.8.1(2025-03-12); clusterProfiler 4.17.0(2025-09-21); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); ComplexHeatmap 2.25.2(2025-09-21); cowplot 1.2.0(2025-07-07); crayon 1.5.3(2024-06-20); curl 7.0.0(2025-08-19); data.table 1.17.8(2025-07-10); DBI 1.2.3(2024-06-02); dbplyr 2.5.1(2025-09-10); DelayedArray 0.35.3(2025-09-21); desc 1.4.3(2023-12-10); dichromat 2.0-0.1(2022-05-02); digest 0.6.37(2024-08-19); doParallel 1.0.17(2022-02-07); DOSE 4.3.0(2025-09-21); dplyr 1.1.4(2023-11-17); DT 0.34.0(2025-09-02); edgeR 4.7.4(2025-09-21); enrichplot 1.29.2(2025-09-21); evaluate 1.0.5(2025-08-27); farver 2.1.2(2024-05-13); fastmap 1.2.0(2024-05-15); fastmatch 1.1-6(2024-12-23); fgsea 1.35.6(2025-09-21); filelock 1.0.3(2023-12-11); fontawesome 0.5.3(2024-11-16); foreach 1.5.2(2022-02-02); fs 1.6.6(2025-04-12); generics 0.1.4(2025-05-09); GenomicAlignments 1.45.4(2025-09-21); GenomicFeatures 1.61.6(2025-09-21); GenomicRanges 1.61.4(2025-09-21); GetoptLong 1.0.5(2020-12-15); ggforce 0.5.0(2025-06-18); ggfun 0.2.0(2025-07-15); ggiraph 0.9.1(2025-09-16); ggplot2 4.0.0(2025-09-11); ggplotify 0.1.3(2025-09-20); ggraph 2.2.2(2025-08-24); ggrepel 0.9.6(2024-09-07); ggridges 0.5.7(2025-08-27); ggtangle 0.0.7(2025-06-30); ggtree 3.99.0(2025-09-21); ggvenn 0.1.10(2023-03-31); gINTomics 1.5.0(2025-09-21); GlobalOptions 0.1.2(2020-06-10); glue 1.8.0(2024-09-30); GO.db 3.21.0(2025-09-10); GOSemSim 2.35.1(2025-09-21); graph 1.87.0(2025-09-21); graphite 1.55.0(2025-09-21); graphlayouts 1.2.2(2025-01-23); gridExtra 2.3(2017-09-09); gridGraphics 0.5-1(2020-12-13); gson 0.1.0(2023-03-07); gtable 0.3.6(2024-10-25); gtools 3.9.5(2023-11-20); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httpuv 1.6.16(2025-04-16); httr 1.4.7(2023-08-15); httr2 1.2.1(2025-07-22); igraph 2.1.4(2025-01-23); InteractiveComplexHeatmap 1.17.0(2025-09-21); IRanges 2.43.2(2025-09-21); iterators 1.0.14(2022-02-05); jsonlite 2.0.0(2025-03-27); kableExtra 1.4.0(2024-01-24); KEGGREST 1.49.1(2025-09-21); knitr 1.50(2025-03-16); later 1.4.4(2025-08-27); lattice 0.22-7(2025-04-02); lazyeval 0.2.2(2019-03-15); lifecycle 1.0.4(2023-11-07); limma 3.65.4(2025-09-21); locfit 1.5-9.12(2025-03-05); logger 0.4.1(2025-09-11); lubridate 1.9.4(2024-12-08); magrittr 2.0.4(2025-09-12); MASS 7.3-65(2025-02-28); Matrix 1.7-4(2025-08-28); MatrixGenerics 1.21.0(2025-09-21); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); MethylMix 2.39.0(2025-09-21); mime 0.13(2025-03-17); MultiAssayExperiment 1.35.9(2025-09-21); nlme 3.1-168(2025-03-31); OmnipathR 3.17.4(2025-09-21); org.Hs.eg.db 3.21.0(2025-09-10); org.Mm.eg.db 3.21.0(2025-09-10); patchwork 1.3.2(2025-08-25); pillar 1.11.1(2025-09-17); pkgconfig 2.0.3(2019-09-22); plotly 4.11.0(2025-06-19); plyr 1.8.9(2023-10-02); png 0.1-8(2022-11-29); polyclip 1.10-7(2024-07-23); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.3(2025-05-29); ps 1.9.1(2025-04-12); purrr 1.1.0(2025-07-10); qvalue 2.41.0(2025-09-21); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.1(2025-05-02); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); randomForest 4.7-1.2(2024-09-22); rappdirs 0.3.3(2021-01-31); RColorBrewer 1.1-3(2022-04-03); Rcpp 1.1.0(2025-07-02); RCurl 1.98-1.17(2025-03-22); reactome.db 1.92.0(2025-09-10); ReactomePA 1.53.0(2025-09-21); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); reshape2 1.4.4(2020-04-09); restfulr 0.0.16(2025-06-27); rjson 0.2.23(2024-09-16); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); Rsamtools 2.25.3(2025-09-21); RSQLite 2.4.3(2025-08-20); rstudioapi 0.17.1(2024-10-22); rtracklayer 1.69.1(2025-09-21); rvest 1.0.5(2025-08-29); S4Arrays 1.9.1(2025-09-21); S4Vectors 0.47.2(2025-09-21); S7 0.2.0(2024-11-07); scales 1.4.0(2025-04-24); Seqinfo 0.99.2(2025-09-21); sessioninfo 1.2.3(2025-02-05); shape 1.4.6.1(2024-02-23); shiny 1.11.1(2025-07-03); shiny.gosling 1.5.0(2025-09-21); shinydashboard 0.7.3(2025-04-21); shinyjs 2.1.0(2021-12-23); SparseArray 1.9.1(2025-09-21); statmod 1.5.0(2023-01-06); stringi 1.8.7(2025-03-27); stringr 1.5.2(2025-09-08); SummarizedExperiment 1.39.2(2025-09-21); svglite 2.2.1(2025-05-12); systemfonts 1.2.3(2025-04-30); testthat 3.2.3(2025-01-13); textshaping 1.0.3(2025-09-02); tibble 3.3.0(2025-06-08); tidygraph 1.3.1(2024-01-30); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); tidytree 0.4.6(2023-12-12); timechange 0.3.0(2024-01-18); treeio 1.33.0(2025-09-21); tweenr 2.0.3(2024-02-26); TxDb.Hsapiens.UCSC.hg38.knownGene 3.21.0(2025-09-10); TxDb.Mmusculus.UCSC.mm10.knownGene 3.10.0(2025-09-10); tzdb 0.5.0(2025-03-15); uuid 1.2-1(2024-07-29); vctrs 0.6.5(2023-12-01); viridis 0.6.5(2024-01-29); viridisLite 0.4.2(2023-05-02); visNetwork 2.1.4(2025-09-04); waldo 0.6.2(2025-07-11); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.53(2025-08-19); XML 3.99-0.19(2025-08-22); xml2 1.4.0(2025-08-20); xtable 1.8-4(2019-04-21); XVector 0.49.1(2025-09-21); yaml 2.3.10(2024-07-26); yulab.utils 0.2.1(2025-08-19); zip 2.3.3(2025-05-13) [2025-09-21 21:52:57] [INFO] [OmnipathR] CURL: version: 8.14.1; headers: 8.14.1; ssl_version: LibreSSL/3.3.6 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE 'select()' returned many:many mapping between keys and columns Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames response_var and covariates have common colnames, adding '_cov' to covariates colnames response_var and covariates have common colnames, adding '_cov' to covariates colnames response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames response_var and covariates have common colnames, adding '_cov' to covariates colnames response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions response_var and covariates have common colnames, adding '_cov' to covariates colnames Generating interactions Generating interactions 'select()' returned many:many mapping between keys and columns [ FAIL 9 | WARN 5 | SKIP 0 | PASS 193 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-downloads.R:6:3'): .download_mirna_target works ──────────────── <purrr_error_indexed/rlang_error/error/condition> Error in `map_int(., ncbi_taxid)`: i In index: 1. i With name: hsa. Caused by error in `map_int()`: i In index: 1. Caused by error in `req_perform()`: ! HTTP 504 Gateway Timeout. Backtrace: ▆ 1. ├─gINTomics:::.download_mirna_target(...) at test-downloads.R:6:3 2. │ └─OmnipathR::import_mirnatarget_interactions(organism = org[species]) 3. │ └─OmnipathR::mirna_target(...) 4. │ ├─rlang::exec(omnipath_query, !!!args) 5. │ └─OmnipathR (local) `<fn>`(organisms = `<dbl>`, query_type = "interactions", datasets = "mirnatarget") 6. │ └─environment() %>% as.list %>% c(list(...)) %>% ... 7. ├─OmnipathR:::omnipath_check_param(.) 8. │ └─param$organisms %<>% map_int(ncbi_taxid) 9. ├─purrr::map_int(., ncbi_taxid) 10. │ └─purrr:::map_("integer", .x, .f, ..., .progress = .progress) 11. │ ├─purrr:::with_indexed_errors(...) 12. │ │ └─base::withCallingHandlers(...) 13. │ ├─purrr:::call_with_cleanup(...) 14. │ └─OmnipathR (local) .f(.x[[i]], ...) 15. │ └─name %>% map_int(taxon_name, "ncbi") %>% as.integer 16. ├─purrr::map_int(., taxon_name, "ncbi") 17. │ └─purrr:::map_("integer", .x, .f, ..., .progress = .progress) 18. │ ├─purrr:::with_indexed_errors(...) 19. │ │ └─base::withCallingHandlers(...) 20. │ ├─purrr:::call_with_cleanup(...) 21. │ └─OmnipathR (local) .f(.x[[i]], ...) 22. │ ├─... %>% if_null_len0(NA) 23. │ └─OmnipathR::get_db("organisms") 24. │ └─OmnipathR::load_db(key, param = param) 25. │ ├─rlang::exec(loader, !!!param) 26. │ └─OmnipathR (local) `<fn>`() 27. │ ├─... %>% ... 28. │ └─OmnipathR::ensembl_organisms() 29. │ ├─... %>% ... 30. │ └─OmnipathR::ensembl_organisms_raw() 31. │ └─... %>% html_table() 32. ├─OmnipathR:::if_null_len0(., NA) 33. │ └─value1 %>% is_empty_2 %>% if (value2) value1 34. ├─OmnipathR:::is_empty_2(.) 35. │ └─value %>% ... 36. ├─dplyr::pull(., name_type) 37. ├─dplyr::filter(...) 38. ├─dplyr::mutate(...) 39. ├─dplyr::full_join(...) 40. ├─dplyr::full_join(...) 41. ├─dplyr::rename(., common_name_ensembl = common_name) 42. ├─dplyr::mutate(...) 43. ├─dplyr::select(...) 44. ├─rvest::html_table(.) 45. ├─rvest::html_element(., "table") 46. ├─xml2::read_html(.) 47. ├─OmnipathR:::download_to_cache(., http_headers = user_agent()) 48. │ └─OmnipathR:::download_base(...) 49. │ └─base::stop(result) 50. ├─purrr (local) `<fn>`(`<ht2__504>`) 51. │ └─cli::cli_abort(...) 52. │ └─rlang::abort(...) 53. │ └─rlang:::signal_abort(cnd, .file) 54. │ └─base::signalCondition(cnd) 55. └─purrr (local) `<fn>`(`<prrr_rr_>`) 56. └─cli::cli_abort(...) 57. └─rlang::abort(...) ── Error ('test-downloads.R:16:3'): .download_tf_mirna works ─────────────────── <purrr_error_indexed/rlang_error/error/condition> Error in `map_int(., ncbi_taxid)`: i In index: 1. i With name: hsa. Caused by error in `map_int()`: i In index: 1. Caused by error in `req_perform()`: ! HTTP 504 Gateway Timeout. Backtrace: ▆ 1. ├─gINTomics:::.download_tf_mirna(...) at test-downloads.R:16:3 2. │ └─OmnipathR::import_tf_mirna_interactions(...) 3. │ └─OmnipathR::tf_mirna(...) 4. │ ├─rlang::exec(omnipath_query, !!!args) 5. │ └─OmnipathR (local) `<fn>`(...) 6. │ └─environment() %>% as.list %>% c(list(...)) %>% ... 7. ├─OmnipathR:::omnipath_check_param(.) 8. │ └─param$organisms %<>% map_int(ncbi_taxid) 9. ├─purrr::map_int(., ncbi_taxid) 10. │ └─purrr:::map_("integer", .x, .f, ..., .progress = .progress) 11. │ ├─purrr:::with_indexed_errors(...) 12. │ │ └─base::withCallingHandlers(...) 13. │ ├─purrr:::call_with_cleanup(...) 14. │ └─OmnipathR (local) .f(.x[[i]], ...) 15. │ └─name %>% map_int(taxon_name, "ncbi") %>% as.integer 16. ├─purrr::map_int(., taxon_name, "ncbi") 17. │ └─purrr:::map_("integer", .x, .f, ..., .progress = .progress) 18. │ ├─purrr:::with_indexed_errors(...) 19. │ │ └─base::withCallingHandlers(...) 20. │ ├─purrr:::call_with_cleanup(...) 21. │ └─OmnipathR (local) .f(.x[[i]], ...) 22. │ ├─... %>% if_null_len0(NA) 23. │ └─OmnipathR::get_db("organisms") 24. │ └─OmnipathR::load_db(key, param = param) 25. │ ├─rlang::exec(loader, !!!param) 26. │ └─OmnipathR (local) `<fn>`() 27. │ ├─... %>% ... 28. │ └─OmnipathR::ensembl_organisms() 29. │ ├─... %>% ... 30. │ └─OmnipathR::ensembl_organisms_raw() 31. │ └─... %>% html_table() 32. ├─OmnipathR:::if_null_len0(., NA) 33. │ └─value1 %>% is_empty_2 %>% if (value2) value1 34. ├─OmnipathR:::is_empty_2(.) 35. │ └─value %>% ... 36. ├─dplyr::pull(., name_type) 37. ├─dplyr::filter(...) 38. ├─dplyr::mutate(...) 39. ├─dplyr::full_join(...) 40. ├─dplyr::full_join(...) 41. ├─dplyr::rename(., common_name_ensembl = common_name) 42. ├─dplyr::mutate(...) 43. ├─dplyr::select(...) 44. ├─rvest::html_table(.) 45. ├─rvest::html_element(., "table") 46. ├─xml2::read_html(.) 47. ├─OmnipathR:::download_to_cache(., http_headers = user_agent()) 48. │ └─OmnipathR:::download_base(...) 49. │ └─base::stop(result) 50. ├─purrr (local) `<fn>`(`<ht2__504>`) 51. │ └─cli::cli_abort(...) 52. │ └─rlang::abort(...) 53. │ └─rlang:::signal_abort(cnd, .file) 54. │ └─base::signalCondition(cnd) 55. └─purrr (local) `<fn>`(`<prrr_rr_>`) 56. └─cli::cli_abort(...) 57. └─rlang::abort(...) ── Error ('test-downloads.R:26:3'): .download_tf works ───────────────────────── <purrr_error_indexed/rlang_error/error/condition> Error in `map_int(., ncbi_taxid)`: i In index: 1. i With name: hsa. Caused by error in `map_int()`: i In index: 1. Caused by error in `req_perform()`: ! HTTP 504 Gateway Timeout. Backtrace: ▆ 1. ├─gINTomics:::.download_tf(genes = colnames(expression), species = species) at test-downloads.R:26:3 2. │ └─OmnipathR::import_tf_target_interactions(organism = org[species]) 3. │ └─OmnipathR::tf_target(...) 4. │ ├─rlang::exec(omnipath_query, !!!args) 5. │ └─OmnipathR (local) `<fn>`(organisms = `<dbl>`, query_type = "interactions", datasets = "tf_target") 6. │ └─environment() %>% as.list %>% c(list(...)) %>% ... 7. ├─OmnipathR:::omnipath_check_param(.) 8. │ └─param$organisms %<>% map_int(ncbi_taxid) 9. ├─purrr::map_int(., ncbi_taxid) 10. │ └─purrr:::map_("integer", .x, .f, ..., .progress = .progress) 11. │ ├─purrr:::with_indexed_errors(...) 12. │ │ └─base::withCallingHandlers(...) 13. │ ├─purrr:::call_with_cleanup(...) 14. │ └─OmnipathR (local) .f(.x[[i]], ...) 15. │ └─name %>% map_int(taxon_name, "ncbi") %>% as.integer 16. ├─purrr::map_int(., taxon_name, "ncbi") 17. │ └─purrr:::map_("integer", .x, .f, ..., .progress = .progress) 18. │ ├─purrr:::with_indexed_errors(...) 19. │ │ └─base::withCallingHandlers(...) 20. │ ├─purrr:::call_with_cleanup(...) 21. │ └─OmnipathR (local) .f(.x[[i]], ...) 22. │ ├─... %>% if_null_len0(NA) 23. │ └─OmnipathR::get_db("organisms") 24. │ └─OmnipathR::load_db(key, param = param) 25. │ ├─rlang::exec(loader, !!!param) 26. │ └─OmnipathR (local) `<fn>`() 27. │ ├─... %>% ... 28. │ └─OmnipathR::ensembl_organisms() 29. │ ├─... %>% ... 30. │ └─OmnipathR::ensembl_organisms_raw() 31. │ └─... %>% html_table() 32. ├─OmnipathR:::if_null_len0(., NA) 33. │ └─value1 %>% is_empty_2 %>% if (value2) value1 34. ├─OmnipathR:::is_empty_2(.) 35. │ └─value %>% ... 36. ├─dplyr::pull(., name_type) 37. ├─dplyr::filter(...) 38. ├─dplyr::mutate(...) 39. ├─dplyr::full_join(...) 40. ├─dplyr::full_join(...) 41. ├─dplyr::rename(., common_name_ensembl = common_name) 42. ├─dplyr::mutate(...) 43. ├─dplyr::select(...) 44. ├─rvest::html_table(.) 45. ├─rvest::html_element(., "table") 46. ├─xml2::read_html(.) 47. ├─OmnipathR:::download_to_cache(., http_headers = user_agent()) 48. │ └─OmnipathR:::download_base(...) 49. │ └─base::stop(result) 50. ├─purrr (local) `<fn>`(`<ht2__504>`) 51. │ └─cli::cli_abort(...) 52. │ └─rlang::abort(...) 53. │ └─rlang:::signal_abort(cnd, .file) 54. │ └─base::signalCondition(cnd) 55. └─purrr (local) `<fn>`(`<prrr_rr_>`) 56. └─cli::cli_abort(...) 57. └─rlang::abort(...) ── Failure ('test-outputs_shiny.R:66:3'): .build_venn works ──────────────────── `venn` has type 'object', not 'list'. ── Failure ('test-outputs_shiny.R:68:3'): .build_venn works ──────────────────── names(venn)[1] (`actual`) not equal to "data" (`expected`). `actual` is NULL `expected` is a character vector ('data') ── Failure ('test-outputs_shiny.R:149:3'): .build_ridge works ────────────────── `tested` has type 'object', not 'list'. ── Failure ('test-outputs_shiny.R:151:3'): .build_ridge works ────────────────── names(tested)[1] (`actual`) not equal to "data" (`expected`). `actual` is NULL `expected` is a character vector ('data') ── Failure ('test-outputs_shiny.R:184:3'): .build_histo works ────────────────── `tested` has type 'object', not 'list'. ── Failure ('test-outputs_shiny.R:186:3'): .build_histo works ────────────────── names(tested)[1] (`actual`) not equal to "data" (`expected`). `actual` is NULL `expected` is a character vector ('data') [ FAIL 9 | WARN 5 | SKIP 0 | PASS 193 ] Error: Test failures Execution halted
gINTomics.Rcheck/gINTomics-Ex.timings
name | user | system | elapsed | |
create_multiassay | 0.866 | 0.138 | 1.127 | |
dot_plotly | 0.976 | 0.111 | 1.709 | |
extract_model_res | 15.380 | 1.538 | 20.248 | |
mirna_hsa | 0.022 | 0.003 | 0.026 | |
mmultiassay_ov | 0.094 | 0.005 | 0.099 | |
plot_chr_distribution | 0.670 | 0.108 | 0.832 | |
plot_heatmap | 0.652 | 0.107 | 0.770 | |
plot_network | 0.660 | 0.109 | 0.777 | |
plot_ridge | 12.064 | 1.418 | 16.194 | |
plot_tf_distribution | 0.719 | 0.117 | 0.896 | |
plot_venn | 0.634 | 0.099 | 0.737 | |