| Back to Build/check report for BioC 3.23: simplified long | 
  | 
This page was generated on 2025-11-03 11:32 -0500 (Mon, 03 Nov 2025).
| Hostname | OS | Arch (*) | R version | Installed pkgs | 
|---|---|---|---|---|
| nebbiolo1 | Linux (Ubuntu 24.04.3 LTS) | x86_64 | R Under development (unstable) (2025-10-20 r88955) -- "Unsuffered Consequences" | 4775 | 
| Click on any hostname to see more info about the system (e.g. compilers) (*) as reported by 'uname -p', except on Windows and Mac OS X | ||||
| Package 58/2321 | Hostname | OS / Arch | INSTALL | BUILD | CHECK | BUILD BIN | ||||||||
| AlphaMissenseR 1.7.0  (landing page) Martin Morgan 
  | nebbiolo1 | Linux (Ubuntu 24.04.3 LTS) / x86_64 | OK | OK | ERROR | |||||||||
| 
To the developers/maintainers of the AlphaMissenseR package: - Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/AlphaMissenseR.git to reflect on this report. See Troubleshooting Build Report for more information. - Use the following Renviron settings to reproduce errors and warnings. - If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.  | 
| Package: AlphaMissenseR | 
| Version: 1.7.0 | 
| Command: /home/biocbuild/bbs-3.23-bioc/R/bin/R CMD check --install=check:AlphaMissenseR.install-out.txt --library=/home/biocbuild/bbs-3.23-bioc/R/site-library --timings AlphaMissenseR_1.7.0.tar.gz | 
| StartedAt: 2025-11-02 20:47:39 -0500 (Sun, 02 Nov 2025) | 
| EndedAt: 2025-11-02 20:53:48 -0500 (Sun, 02 Nov 2025) | 
| EllapsedTime: 368.6 seconds | 
| RetCode: 1 | 
| Status: ERROR | 
| CheckDir: AlphaMissenseR.Rcheck | 
| Warnings: NA | 
##############################################################################
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###
### Running command:
###
###   /home/biocbuild/bbs-3.23-bioc/R/bin/R CMD check --install=check:AlphaMissenseR.install-out.txt --library=/home/biocbuild/bbs-3.23-bioc/R/site-library --timings AlphaMissenseR_1.7.0.tar.gz
###
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##############################################################################
* using log directory ‘/home/biocbuild/bbs-3.23-bioc/meat/AlphaMissenseR.Rcheck’
* using R Under development (unstable) (2025-10-20 r88955)
* using platform: x86_64-pc-linux-gnu
* R was compiled by
    gcc (Ubuntu 13.3.0-6ubuntu2~24.04) 13.3.0
    GNU Fortran (Ubuntu 13.3.0-6ubuntu2~24.04) 13.3.0
* running under: Ubuntu 24.04.3 LTS
* using session charset: UTF-8
* checking for file ‘AlphaMissenseR/DESCRIPTION’ ... OK
* this is package ‘AlphaMissenseR’ version ‘1.7.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘AlphaMissenseR’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking loading without being on the library search path ... OK
* checking whether startup messages can be suppressed ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
            user system elapsed
db        11.567  1.039   3.977
AlphaFold  7.454  1.294  35.855
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking re-building of vignette outputs ... ERROR
Error(s) in re-building vignettes:
--- re-building ‘alphafold.Rmd’ using rmarkdown
--- finished re-building ‘alphafold.Rmd’
--- re-building ‘benchmarking.Rmd’ using rmarkdown
--- finished re-building ‘benchmarking.Rmd’
--- re-building ‘clinvar.Rmd’ using rmarkdown
--- finished re-building ‘clinvar.Rmd’
--- re-building ‘introduction.Rmd’ using rmarkdown
Quitting from introduction.Rmd:220-225 [ahub-homo-sap]
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
<error/rlang_error>
Error in `value[[3L]]()`:
! failed to connect
  reason: Failed to perform HTTP request.
Caused by error in `curl::curl_fetch_memory()`:
! Timeout was reached [bioconductor.org]:
SSL connection timeout
  Consider rerunning with 'localHub=TRUE'
---
Backtrace:
    ▆
 1. └─AnnotationHub::AnnotationHub()
 2.   └─AnnotationHub::.Hub(...)
 3.     └─base::tryCatch(...)
 4.       └─base (local) tryCatchList(expr, classes, parentenv, handlers)
 5.         └─base (local) tryCatchOne(expr, names, parentenv, handlers[[1L]])
 6.           └─value[[3L]](cond)
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Error: processing vignette 'introduction.Rmd' failed with diagnostics:
failed to connect
  reason: Failed to perform HTTP request.
Caused by error in `curl::curl_fetch_memory()`:
! Timeout was reached [bioconductor.org]:
SSL connection timeout
  Consider rerunning with 'localHub=TRUE'
--- failed re-building ‘introduction.Rmd’
--- re-building ‘issues.Rmd’ using rmarkdown
Quitting from issues.Rmd:73-75 [unnamed-chunk-4]
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
<error/rlang_error>
Error in `file()`:
! cannot open the connection to 'https://zenodo.org/api/records/10813168/versions/latest'
---
Backtrace:
     ▆
  1. └─AlphaMissenseR::am_data("gene_hg38")
  2.   └─AlphaMissenseR::am_available(record = record)
  3.     └─AlphaMissenseR:::am_available_from_internet(record, bfc)
  4.       ├─AlphaMissenseR:::am_record_is_latest(record)
  5.       │ ├─base::withVisible(eval(mc, parent.frame()))
  6.       │ └─base::eval(mc, parent.frame())
  7.       │   └─base::eval(mc, parent.frame())
  8.       └─AlphaMissenseR (local) `<fn>`(record = record)
  9.         └─base::readLines(latest_version_url, warn = FALSE)
 10.           └─base::file(con, "r")
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Error: processing vignette 'issues.Rmd' failed with diagnostics:
cannot open the connection to 'https://zenodo.org/api/records/10813168/versions/latest'
--- failed re-building ‘issues.Rmd’
SUMMARY: processing the following files failed:
  ‘introduction.Rmd’ ‘issues.Rmd’
Error: Vignette re-building failed.
Execution halted
* checking PDF version of manual ... OK
* DONE
Status: 1 ERROR
See
  ‘/home/biocbuild/bbs-3.23-bioc/meat/AlphaMissenseR.Rcheck/00check.log’
for details.
AlphaMissenseR.Rcheck/00install.out
############################################################################## ############################################################################## ### ### Running command: ### ### /home/biocbuild/bbs-3.23-bioc/R/bin/R CMD INSTALL AlphaMissenseR ### ############################################################################## ############################################################################## * installing to library ‘/home/biocbuild/bbs-3.23-bioc/R/site-library’ * installing *source* package ‘AlphaMissenseR’ ... ** this is package ‘AlphaMissenseR’ version ‘1.7.0’ ** using staged installation ** R ** inst ** byte-compile and prepare package for lazy loading ** help *** installing help indices ** building package indices ** installing vignettes ** testing if installed package can be loaded from temporary location ** testing if installed package can be loaded from final location ** testing if installed package keeps a record of temporary installation path * DONE (AlphaMissenseR)
AlphaMissenseR.Rcheck/tests/testthat.Rout
R Under development (unstable) (2025-10-20 r88955) -- "Unsuffered Consequences"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu
R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.
R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.
Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.
> # This file is part of the standard setup for testthat.
> # It is recommended that you do not modify it.
> #
> # Where should you do additional test configuration?
> # Learn more about the roles of various files in:
> # * https://r-pkgs.org/testing-design.html#sec-tests-files-overview
> # * https://testthat.r-lib.org/articles/special-files.html
> 
> library(testthat)
> library(AlphaMissenseR)
Loading required package: dplyr
Attaching package: 'dplyr'
The following object is masked from 'package:testthat':
    matches
The following objects are masked from 'package:stats':
    filter, lag
The following objects are masked from 'package:base':
    intersect, setdiff, setequal, union
> 
> test_check("AlphaMissenseR")
* [20:49:57][info] disconnecting all registered connections
[ FAIL 0 | WARN 0 | SKIP 0 | PASS 128 ]
> 
> proc.time()
   user  system elapsed 
 24.017   2.246  38.081 
AlphaMissenseR.Rcheck/AlphaMissenseR-Ex.timings
| name | user | system | elapsed | |
| AlphaFold | 7.454 | 1.294 | 35.855 | |
| AlphaMissense | 1.368 | 0.096 | 1.413 | |
| ClinVar | 4.843 | 0.147 | 4.845 | |
| GenomicRanges | 4.713 | 0.218 | 4.001 | |
| Gosling | 3.578 | 0.588 | 1.569 | |
| am_aa | 3.642 | 0.034 | 1.139 | |
| db | 11.567 | 1.039 | 3.977 | |