caradpt: Covariate-Adjusted Response-Adaptive Designs for Clinical Trials
Tools for implementing covariate-adjusted response-adaptive procedures for binary, continuous and survival responses. Users can flexibly choose between two functions based on their specific needs for each procedure: use real patient data from clinical trials to compute allocation probabilities directly, or use built-in simulation functions to generate synthetic patient data. Detailed methodologies and algorithms used in this package are described in the following references:
Zhang, L. X., Hu, F., Cheung, S. H., & Chan, W. S. (2007)<doi:10.1214/009053606000001424>
Zhang, L. X. & Hu, F. (2009) <doi:10.1007/s11766-009-0001-6>
Hu, J., Zhu, H., & Hu, F. (2015) <doi:10.1080/01621459.2014.903846>
Zhao, W., Ma, W., Wang, F., & Hu, F. (2022) <doi:10.1002/pst.2160>
Mukherjee, A., Jana, S., & Coad, S. (2024) <doi:10.1177/09622802241287704>.
Version: |
0.1.0 |
Depends: |
R (≥ 3.6.0) |
Imports: |
survival |
Published: |
2025-08-28 |
Author: |
Renjie Luo [aut, cre],
Feifang Hu [aut, ctb] |
Maintainer: |
Renjie Luo <jerry.luorj at gmail.com> |
License: |
GPL-3 |
NeedsCompilation: |
no |
CRAN checks: |
caradpt results |
Documentation:
Downloads:
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