Calibration, Validation, and Simulation of TKTD Models


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Documentation for package ‘cvasi’ version 1.5.0

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A B C D E F G I L M N P R S T misc

-- A --

Algae-class Algae models
Algae-models Algae models
AlgaeSimple-class Simple algae model without environment (Rendal et al. 2023)
AlgaeSimpleScenario-class Simple algae model without environment (Rendal et al. 2023)
AlgaeTKTD-class Algae model variant (Weber et al. 2012) with scaled damage
AlgaeTKTDScenario-class Algae model variant (Weber et al. 2012) with scaled damage
AlgaeWeber-class Algae model, _SAM-X_ (Weber et al. 2012)
AlgaeWeberScenario-class Algae model, _SAM-X_ (Weber et al. 2012)
Algae_Simple Simple algae model without environment (Rendal et al. 2023)
Algae_TKTD Algae model variant (Weber et al. 2012) with scaled damage
Algae_Weber Algae model, _SAM-X_ (Weber et al. 2012)
americamysis A DEB abj scenario of Americamysis bahia

-- B --

batch Batch simulation of multiple exposure levels
Biomass-transfer Biomass transfer class

-- C --

cache_controls Cache control simulations
calibrate Fit model parameters to experimental data
calibrate-method Fit model parameters to experimental data
CalibrationSet Calibration set
CalibrationSet-class Calibration set
caliset Calibration set
ci_from_hessian Parameter confidence intervals from fit

-- D --

Deb-class Dynamic Energy Budget (DEB) models
DEB-models Dynamic Energy Budget (DEB) models
DebAbj-class DEB_abj
DebDaphnia-class DEBtox model
DEBtox DEBtox model
DebTox-class DEBtox model
DEBtox2019 DEBtox model
DEB_abj DEB_abj
DEB_Daphnia DEBtox model
diagnostics Diagnostics of solvers
diagnostics.cvasi_simulate Diagnostics of solvers
diagnostics.default Diagnostics of solvers
dmagna A DEBtox scenario of Daphnia magna
dose_response Calculate a dose response curve

-- E --

effect Effect level
effect-method Effect level
EffectScenario-class Effect scenario classes
epx Effect profiles (EPx values)
epx_mtw Calculate EPx values for a series of moving time window
explore_space Explore parameter space
ExposureSeries Exposure time-series
ExposureSeries-class Exposure time-series

-- F --

fit_growth Fit growth parameters
fit_growth-method Fit growth parameters
fit_tktd Fit TK/TD parameters
fit_tktd-method Fit TK/TD parameters
focusd1 A Lemna_SETAC scenario with variable environment
fx Generic to calculate effects for a particular scenario
fx-method Generic to calculate effects for a particular scenario

-- G --

get_model Get model name
get_model-method Get model name
get_model_name Get model name
get_param Get scenario parameters
get_param-method Get scenario parameters
get_tag Get scenario tag
get_tag-method Get scenario tag
get_times Get output times
get_times-method Get output times
Guts-class GUTS-SD scenario
GUTS-IT GUTS-IT scenario
GUTS-RED-IT GUTS-RED-IT scenario
GUTS-RED-models GUTS-RED models
GUTS-RED-SD GUTS-RED-SD scenario
GUTS-SD GUTS-SD scenario
GutsIt-class GUTS-IT scenario
GutsRedIt-class GUTS-RED-IT scenario
GutsRedSd-class GUTS-RED-SD scenario
GutsSd-class GUTS-SD scenario
GUTS_IT GUTS-IT scenario
GUTS_RED_IT GUTS-RED-IT scenario
GUTS_RED_SD GUTS-RED-SD scenario
GUTS_SD GUTS-SD scenario

-- I --

import_morse Import 'morse' model parameters
import_swash SWASH project exposure profile import
import_toxswa Import _TOXSWA_ exposure series
is_DEB Test if argument is a DEB scenario
is_deb Test if argument is a DEB scenario
is_GUTS Test if argument is a GUTS scenario
is_guts Test if argument is a GUTS scenario
is_GUTS_IT Test if argument is a GUTS scenario
is_guts_it Test if argument is a GUTS scenario
is_GUTS_SD Test if argument is a GUTS scenario
is_guts_sd Test if argument is a GUTS scenario
is_Lemna Test if argument is a Lemna scenario
is_lemna Test if argument is a Lemna scenario
is_LemnaThreshold Test if argument is a LemnaThreshold scenario
is_scenario Test if argument is an effect scenario

-- L --

Lemna-class Lemna models
Lemna-models Lemna models
LemnaSchmitt-class Lemna model (Schmitt et al. 2013)
LemnaSchmittScenario-class Lemna model (Schmitt et al. 2013)
LemnaSetac-class Lemna model v1.3 (Klein et al. 2021)
LemnaSetacScenario-class Lemna model v1.3 (Klein et al. 2021)
Lemna_Schmitt Lemna model (Schmitt et al. 2013)
Lemna_SchmittThold Lemna model (Schmitt et al. 2013)
Lemna_SETAC Lemna model v1.3 (Klein et al. 2021)
length-method Extract and replace elements of a sequence
lik_profile Likelihood profiling
log_disable Start and stop logging
log_enable Start and stop logging
log_envir Log R environment properties
log_lik Calculate log likelihood
log_msg Add a log message
log_scenarios Log scenario properties

-- M --

Macrophyte-models Macrophyte models
Magma Magma model (Witt et al., submitted)
Magma-class Magma scenario class
metsulfuron Lemna model fitted to _metsulfuron_ effect data
minnow_it A fitted GUTS-RED-IT scenario of the fathead minnow
minnow_sd A fitted GUTS-RED-SD scenario of the fathead minnow
morse Import 'morse' model parameters
Myrio Magma model (Witt et al., submitted)
Myrio_log Magma model (Witt et al., submitted)

-- N --

NoExposureSeries-class Exposure time-series
no_exposure Zero exposure
num_info Print information about numerical solver result
num_info.cvasi_fit Print information about numerical solver result
num_info.cvasi_simulate Print information about numerical solver result
num_info.default Print information about numerical solver result

-- P --

ParameterSet-class Set of model parameters
parameter_set Set of model parameters
parameter_set-class Set of model parameters
pll_debug Disable parallelization for debugging
plot S3 plotting functions
plot.cvasi_drc S3 plotting functions
plot.cvasi_simulate S3 plotting functions
plot.lik_profile S3 plotting functions
plot.param_space Plot profiled parameter space
plot_epx Plot EPx values
plot_lik_profile S3 plotting functions
plot_param_space Plot profiled parameter space
plot_ppc Creates a PPC plot for a single dataset
plot_ppc_combi Create PPC plot for one or more datasets
plot_scenario Creates a prediction plot for one effect scenario
plot_sd Creates plot of model results (uncertainties optional)
pull_metadata Pull metadata from scenarios

-- R --

ringtest_c EFSA Ringtest Dataset C
ringtest_it EFSA Ringtest Dataset A SD
ringtest_sd EFSA Ringtest Dataset A SD
rsubcapitata A Weber scenario of algae exposed to isoproturon

-- S --

SAM-X Algae model, _SAM-X_ (Weber et al. 2012)
SamX Algae model, _SAM-X_ (Weber et al. 2012)
scenario Effect scenario classes
Scenarios Effect scenario classes
scenarios Effect scenario classes
ScenarioSequence-class Sequence of scenarios
schmitt2013 A Lemna effect study data set with multiple treatment levels
sequence Sequence of scenarios
sequence.extract Extract and replace elements of a sequence
set_bounds Set boundaries of model parameters
set_bounds-method Set boundaries of model parameters
set_endpoints Set effect endpoints
set_exposure Set exposure time-series
set_exposure-method Set exposure time-series
set_forcings Set time-dependent parameters
set_forcings-method Set time-dependent parameters
set_init Set initial state
set_init-method Set initial state
set_moa Set mode of action
set_mode_of_action Set mode of action
set_noexposure Set zero exposure
set_notransfer Set transfer events
set_nowindow Set window length
set_param Set scenario parameters
set_param-method Set scenario parameters
set_tag Set a tag
set_times Set output times
set_times-method Set output times
set_transfer Set transfer events
set_transfer-method Set transfer events
set_window Set window length
simulate Simulate an effect scenario
simulate-method Simulate an effect scenario
simulate_batch Batch simulation using multiple exposure series
solver Calls ODE solver for a particular model
solver-method Calls ODE solver for a particular model
survival Survival rate

-- T --

td2cs Create _calisets_ from _tox_data_
ToxData-class Prepare ecotox study data for fitting
tox_data Prepare ecotox study data for fitting
Transferable Biomass transfer class
Transferable-class Biomass transfer class

-- misc --

[-method Extract and replace elements of a sequence
[[-method Extract and replace elements of a sequence
[[<--method Extract and replace elements of a sequence