Visualization of Clonal Expansion for Single Cell Immune Profiles


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Documentation for package ‘APackOfTheClones’ version 1.3.0

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AdjustAPOTC Adjust the parameters of the APackOfTheClones reduction in a seurat object
APOTCPlot Various variations of visualizations of clonal expansion post-RunAPOTC
combined_pbmc Example Multi-sampled T-cell seurat object with integrated TCR library
containsApotcRun Check for the existence of an APackOfTheClones run with its run id
countCloneSizes count the number of clonotype sizes in a seurat object combined with a VDJ library overall or by cluster
deleteApotcData Delete the results of an APackOfTheClones run
getApotcDataIds Get all run ids of previous RunAPOTC runs on a seurat object
getApotcRunIds Get all run ids of previous RunAPOTC runs on a seurat object
getLastApotcDataId Get the object id of the most recent RunAPOTC run on a seurat object
getLastApotcRunId Get the object id of the most recent RunAPOTC run on a seurat object
getReductionCentroids Calculate seurat cluster centroids based on a Dimensional reduction
getSharedClones Compute a list of clonotypes that are shared between seurat clusters
mergeCloneSizes Merge a list of Clustered Clonotype Frequency Tables
overlayLegend overlay a clone size legend on an APackOfTheClones plot
removeLegend Remove current APackOfTheClones legend
renameApotcRun Rename an APackOfTheClones run
RunAPOTC Run the APackOfTheClones method on a combined Seurat object for downstream visualization of clonal expansion
showCloneHighlight Highlight specific clones on an APackOfTheClones ggplot
updateApotc Update APackOfTheClones objects to the latest format
vizAPOTC Directly visualize clonal expansion of a combined seurat object