--- title: "stIHC: Spatial transcriptomics iterative hierarchical clustering" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{stIHC-introduction} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r, include = FALSE} knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) ``` ## Overview The stIHC package implements the spatial transcriptomics iterative hierarchical clustering method from the paper Higgins C, Li JJ, Carey M. Spatial transcriptomics iterative hierarchical clustering (stIHC): a novel method for identifying spatial gene co-expression modules. Quantitative Biology. 2025;e70011. https://doi.org/10.1002/qub2.70011 ## Example An example demonstrating how to use stIHC, along with the data required to reproduce simulations from Section 3.2 in our paper, is provided. ```{r setup} library(stIHC) rds_path <- system.file("extdata", "spatial_data.rds", package = "stIHC") example_data <- readRDS(rds_path) stihc = stIHC(example_data) #Run stIHC table(stihc$label) ```