Surrogate Functional False Discovery Rates for Genome-Wide Association Studies

---

Documentation for package ‘sffdr’ version 1.1.2

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

bmi	Subset of p-values from the UK Biobank
decorrelate_informative	Soft whitening of informative trait z-scores
discover_empirical_nulls	Discover Empirical Negative Controls
estimate_rho_overlap	Estimate sample overlap correlation
fpi0est	Estimate Functional Proportion of Null Tests
fpvalues	Functional p-values
kernelEstimator	Kernel Density Estimation for GWAS P-values
monoSmooth_conditional	Fast Conditional Monotonic Smoothing
monoSmooth_pava	Fast Conditional PAVA (Decreasing)
overlap_null_density	Compute conditional null density under sample overlap
pi0_model	Build Model for Functional Proportion of Null Tests (fpi0)
plot,	Plotting function for sffdr object
plot.sffdr	Plotting function for sffdr object
run_empirical_overlap_correction	Run Overlap Correction using Data-Driven Nulls
sffdr	Surrogate Functional False Discovery Rate Analysis
sumstats	Subset of p-values from the UK Biobank