1 Introduction

This document explains the functionalities available in the a4Preproc package.

This package contains utility functions to pre-process data for the Automated Affymetrix Array Analysis suite of packages.

2 Get feature annotation for an ExpressionSet

The feature annotation for a specific dataset, as required by the pipeline is extracted with the addGeneInfo function.

library(ALL)
data(ALL)
a4ALL <- addGeneInfo(eset = ALL)
print(head(fData(a4ALL)))
##           ENTREZID       ENSEMBLID  SYMBOL
## 1000_at       5595 ENSG00000102882   MAPK3
## 1001_at       7075 ENSG00000066056    TIE1
## 1002_f_at     1557 ENSG00000165841 CYP2C19
## 1003_s_at      643 ENSG00000160683   CXCR5
## 1004_at        643 ENSG00000160683   CXCR5
## 1005_at       1843 ENSG00000120129   DUSP1
##                                                                  GENENAME
## 1000_at                                mitogen-activated protein kinase 3
## 1001_at   tyrosine kinase with immunoglobulin like and EGF like domains 1
## 1002_f_at                  cytochrome P450 family 2 subfamily C member 19
## 1003_s_at                                C-X-C motif chemokine receptor 5
## 1004_at                                  C-X-C motif chemokine receptor 5
## 1005_at                                    dual specificity phosphatase 1
print(head(featureData(a4ALL)))
## An object of class 'AnnotatedDataFrame'
##   featureNames: 1000_at 1001_at ... 1005_at (6 total)
##   varLabels: ENTREZID ENSEMBLID SYMBOL GENENAME
##   varMetadata: labelDescription

3 Appendix

3.1 Session information

## R version 4.6.0 RC (2026-04-17 r89917)
## Platform: x86_64-pc-linux-gnu
## Running under: Ubuntu 24.04.4 LTS
## 
## Matrix products: default
## BLAS:   /home/biocbuild/bbs-3.24-bioc/R/lib/libRblas.so 
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0  LAPACK version 3.12.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_GB              LC_COLLATE=C              
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: America/New_York
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] hgu95av2.db_3.13.0   org.Hs.eg.db_3.23.1  AnnotationDbi_1.73.1
##  [4] IRanges_2.45.0       S4Vectors_0.49.2     ALL_1.53.0          
##  [7] Biobase_2.71.0       BiocGenerics_0.57.1  generics_0.1.4      
## [10] a4Preproc_1.59.0    
## 
## loaded via a namespace (and not attached):
##  [1] bit_4.6.0         jsonlite_2.0.0    compiler_4.6.0    crayon_1.5.3     
##  [5] blob_1.3.0        Biostrings_2.79.5 jquerylib_0.1.4   Seqinfo_1.1.0    
##  [9] png_0.1-9         yaml_2.3.12       fastmap_1.2.0     R6_2.6.1         
## [13] XVector_0.51.0    knitr_1.51        DBI_1.3.0         bslib_0.10.0     
## [17] rlang_1.2.0       KEGGREST_1.51.1   cachem_1.1.0      xfun_0.57        
## [21] sass_0.4.10       bit64_4.6.0-1     otel_0.2.0        RSQLite_2.4.6    
## [25] memoise_2.0.1     cli_3.6.6         digest_0.6.39     lifecycle_1.0.5  
## [29] vctrs_0.7.3       evaluate_1.0.5    rmarkdown_2.31    httr_1.4.8       
## [33] tools_4.6.0       pkgconfig_2.0.3   htmltools_0.5.9