Changes in version 1.3.7 - Change the license from Artistic-2.0 to GPL (≥ 2) Changes in version 1.3.6 - Core functions for optimization, bootstrapping, and FDR calculation have been reimplemented and refactored for greater efficiency and faster execution. Changes in version 1.2.2 - Adding Citation and Disclaimer Information Changes in version 0.99.0 - Submitted to Bioconductor