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###
### Running command:
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###   /Library/Frameworks/R.framework/Resources/bin/R CMD build --keep-empty-dirs --no-resave-data iNETgrate
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* checking for file ‘iNETgrate/DESCRIPTION’ ... OK
* preparing ‘iNETgrate’:
* checking DESCRIPTION meta-information ... OK
* installing the package to build vignettes
* creating vignettes ... ERROR
--- re-building ‘iNETgrate_inference.Rnw’ using knitr
2025-10-26 16:55:47.546 R[46435:550334098] XType: Using static font registry.

Quitting from iNETgrate_inference.Rnw:400-408 [pathway_analysis]
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
<error/rlang_error>
Error in `file()`:
! cannot open the connection to 'https://rest.kegg.jp/link/hsa/pathway'
---
Backtrace:
     x
  1. \-Pigengene::get.enriched.pw(...)
  2.   \-Pigengene::get.enriched.pw(...)
  3.     \-clusterProfiler::enrichKEGG(...)
  4.       \-clusterProfiler:::prepare_KEGG(species, "KEGG", keyType)
  5.         \-clusterProfiler::download_KEGG(species, KEGG_Type, keyType)
  6.           \-clusterProfiler:::download.KEGG.Path(species)
  7.             \-clusterProfiler:::kegg_link(species, "pathway")
  8.               \-clusterProfiler:::kegg_rest(url)
  9.                 \-yulab.utils::yread(rest_url)
 10.                   +-base::do.call(reader, args = c(file, params))
 11.                   \-base (local) `<fn>`("https://rest.kegg.jp/link/hsa/pathway")
 12.                     \-base::file(con, "r")
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Error: processing vignette 'iNETgrate_inference.Rnw' failed with diagnostics:
cannot open the connection to 'https://rest.kegg.jp/link/hsa/pathway'
--- failed re-building ‘iNETgrate_inference.Rnw’

SUMMARY: processing the following file failed:
  ‘iNETgrate_inference.Rnw’

Error: Vignette re-building failed.
Execution halted