Bioconductor release scheduled for October 29

BreastSubtypeR

This is the development version of BreastSubtypeR; for the stable release version, see BreastSubtypeR.

Cohort-aware methods for intrinsic molecular subtyping of breast cancer


Bioconductor version: Development (3.22)

BreastSubtypeR provides an assumption-aware, multi-method framework for intrinsic molecular subtyping of breast cancer. The package harmonizes several published nearest-centroid (NC) and single-sample predictor (SSP) classifiers, supplies method-specific preprocessing and robust probe-to-gene mapping, and implements a cohort-aware AUTO mode that selectively enables classifiers compatible with the cohort composition. A local Shiny app (iBreastSubtypeR) is included for interactive analyses and to support users without programming experience.

Author: Qiao Yang [aut, cre] ORCID iD ORCID: 0000-0002-4098-3246 , Emmanouil Sifakis [aut] ORCID iD ORCID: 0000-0001-9919-4471

Maintainer: Qiao Yang <yq.kiuo at gmail.com>

Citation (from within R, enter citation("BreastSubtypeR")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("BreastSubtypeR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BreastSubtypeR")
BreastSubtypeR: Introduction and Workflow HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Classification, GeneExpression, Preprocessing, RNASeq, Software, Visualization
Version 1.1.5
In Bioconductor since BioC 3.21 (R-4.5) (< 6 months)
License GPL-3
Depends R (>= 4.5.0)
Imports methods, Biobase, tidyselect, dplyr, ggplot2, magrittr, rlang, stringr, withr, edgeR, ComplexHeatmap, impute(>= 1.80.0), data.table (>= 1.16.0), RColorBrewer (>= 1.1-3), circlize (>= 0.4.16), ggrepel (>= 0.9.6), e1071 (>= 1.7-8), SummarizedExperiment, utils
System Requirements
URL https://doi.org/10.1093/nargab/lqaf131 https://github.com/yqkiuo/BreastSubtypeR
Bug Reports https://github.com/yqkiuo/BreastSubtypeR/issues
See More
Suggests lifecycle, tidyverse, shiny (>= 1.9.1), bslib (>= 0.8.0), BiocStyle, knitr, rmarkdown, testthat
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BreastSubtypeR_1.1.5.tar.gz
Windows Binary (x86_64) BreastSubtypeR_1.1.2.zip
macOS Binary (x86_64) BreastSubtypeR_1.1.5.tgz
macOS Binary (arm64) BreastSubtypeR_1.1.5.tgz
Source Repository git clone https://git.bioconductor.org/packages/BreastSubtypeR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/BreastSubtypeR
Bioc Package Browser https://code.bioconductor.org/browse/BreastSubtypeR/
Package Short Url https://bioconductor.org/packages/BreastSubtypeR/
Package Downloads Report Download Stats