## ----message=FALSE------------------------------------------------------------ library(trialr) ## ---- results = "hide"-------------------------------------------------------- fit <- stan_hierarchical_response_thall( group_responses = c(0, 0, 1, 3, 5, 0, 1, 2, 0, 0), group_sizes = c(0, 2 ,1, 7, 5, 0, 2, 3, 1, 0), mu_mean = -1.3863, mu_sd = sqrt(1 / 0.1), tau_alpha = 2, tau_beta = 20) ## ----------------------------------------------------------------------------- fit ## ----------------------------------------------------------------------------- knitr::kable(rstan::summary(fit, par = 'prob_response')$summary, digits = 3) ## ----------------------------------------------------------------------------- colMeans(as.data.frame(fit, pars = 'prob_response') > 0.3) ## ---- message = FALSE, fig.width = 7, fig.height = 7, fig.cap = "Prob(Response | D) in subgroup 3"---- library(ggplot2) library(rstan) library(dplyr) plot(fit, pars = 'prob_response') + geom_vline(xintercept = 0.3, col = 'orange', linetype = 'dashed') + labs(title = 'Partially-pooled analysis of response rate in 10 sarcoma subtypes')