\name{lowFilter-methods} \docType{methods} \alias{lowFilter-methods} \alias{lowFilter} \alias{lowFilter<-} \title{Lower Threshold Filter} \description{ This method initializes the Lower Threshold Filter. The \code{cutoff} value defines the lower threshold for allowed expression levels. If e.g. the number of samples lower than this cutoff value is greater than \code{parameter} then the corresponding dataframe row is flagged, i.e. \code{flag = 0}. \cr The Lower Threshold Filter flags all rows with: \code{flag = (sum(expression[i] >= cutoff) >= parameter)} \emph{Usage} \code{lowFilter(object)} \cr \code{lowFilter(object, value)<-} } \arguments{ \item{object}{object of class \code{PreFilter}.} \item{value}{character vector \code{c(cutoff, parameter, condition)}.} } \details{ The method \code{lowFilter} initializes the following parameters: \tabular{lll}{ \tab \code{cutoff}:\tab the lower threshold level for the filter. \cr \tab \code{parameter}:\tab this value depends on the \code{condition} used: \cr \tab \code{condition}:\tab \code{condition="samples"}: number of samples (default): \cr \tab \tab \code{condition="percent"}: percent of samples. \cr \tab \tab \code{condition="mean"}: mean value of samples. \cr \tab \tab \code{condition="percentile"}: percentile of samples. } } \value{ An initialized \code{\linkS4class{PreFilter}} object. } \author{Christian Stratowa} \examples{ prefltr <- PreFilter() lowFilter(prefltr) <- c(4.0,3,"samples") str(prefltr) } \keyword{methods}