\name{MethAlignNW} \alias{MethAlignNW} \title{Summary of methylation states} \description{ Summarize the methylation states after calculating pairwise alignments of each examined sequences and the genomic sequence} \usage{ MethAlignNW(refSeq, QCdata, alignment) } \arguments{ \item{refSeq}{String; Genomic sequence as String format} \item{QCdata}{Data frame; Names and paths of analysed sequences after quality control} \item{alignment}{ If TRUE, alignments are included in summery, else not included} } \details{ Given aligned sequences after quality control, the function returns a list object with the following data: sequences name, methylation state on CpG position, start and end position of alignments and length of genomic sequence. The data includes the core information for the exploratory analysis and visualizations. } \value{ Returns a summery on sequence alignments and methylation states } \author{Arie Zackay , Christine Steinhoff } \examples{ ## In order to use the following example ## make sure that you have writing permission under R.home() ## directory. If you do not have permission choose your own path. dir.create(file.path(R.home(component="home"),"/BiqAnalyzer")) makeLocalExpDir(dataPath="/examples/BiqAnalyzer", localDir=file.path(R.home(component="home"),"/BiqAnalyzer")) datameth <-MethDataInput(file.path(R.home(component="home"), "/BiqAnalyzer/PathFileTab.txt")) refseq <- selectRefSeq(file.path(R.home(component="home"), "/BiqAnalyzer/Master_Sequence.txt")) QCdata <- MethylQC(refseq, datameth) methData <- MethAlignNW( refseq , QCdata) } \keyword{graphs}