\name{deGenes2by2Ttest} \alias{deGenes2by2Ttest} \title{ Function to do differential expression analysis, comparing only two samples } \description{ This function takes an object of class \code{\link{maiges}} and do differential expression analysis for the genes onto dataset, comparing only two samples, by t test. } \usage{ deGenes2by2Ttest(data=NULL, sLabelID=names(data@Slabels)[1], sTypeComp=NULL, doClust=TRUE, \dots) } \arguments{ \item{data}{object of class \code{\link{maiges}}.} \item{sLabelID}{character string giving the sample label ID to be used.} \item{sTypeComp}{list with character vectors specifying the two sample types to be compared.} \item{doClust}{logical indicating if the object generated from this analysis will be used for cluster analysis. Defaults to TRUE.} \item{\dots}{additional parameters for function \code{\link[stats]{t.test}}.} } \value{ The result of this function is an object of class \code{\link{maigesDE}} if \code{doClust} if FALSE or of class \code{\link{maigesDEcluster}} if it is TRUE. } \details{ This function calculate t statistics and p-values for the test of difference in the means of the groups using the function \code{\link[stats]{t.test}}. There are other two functions, \code{\link{deGenes2by2Wilcox}} and \code{\link{deGenes2by2BootT}}, to do non-parametric tests by the Wilcox test an t statistic bootstrap, respectively. } \seealso{ \code{\link[stats]{t.test}}, \code{\link{deGenes2by2Wilcox}} and \code{\link{deGenes2by2BootT}}. } \examples{ ## Loading the dataset data(gastro) ## Doing t test fot 'Type' sample label gastro.ttest = deGenes2by2Ttest(gastro.summ, sLabelID="Type") gastro.ttest } \author{ Gustavo H. Esteves <\email{gesteves@vision.ime.usp.br}> } \keyword{methods}