\name{normexp.signal} \alias{normexp.signal} \title{Expected Signal Given Observed Foreground Under Normal+Exp Model} \description{ Adjust foreground intensities for observed background using Normal+Exp Model. This function is called by \code{backgroundCorrect} and is not normally called directly by the user. } \usage{ normexp.signal(par, x) } \arguments{ \item{par}{numeric vector containing the parameters of the Normal+Exp distribution, see \code{\link{normexp.fit}} for details.} \item{x}{numeric vector of (background corrected) intensities} } \details{ In general the vector \code{normmean} is computed conditional on background at each spot. } \value{ Numeric vector containing adjusted intensities. } \references{ Ritchie, M. E., Silver, J., Oshlack, A., Silver, J., Holmes, M., Diyagama, D., Holloway, A., and Smyth, G. K. (2007). A comparison of background correction methods for two-colour microarrays. \emph{Bioinformatics} \url{http://bioinformatics.oxfordjournals.org/cgi/content/abstract/btm412} Silver, JD, Ritchie, ME, and Smyth, GK (2009). Microarray background correction: maximum likelihood estimation for the normal-exponential convolution. \emph{Biostatistics} 10, 352-363. \url{http://biostatistics.oxfordjournals.org/cgi/content/abstract/kxn042} } \author{Gordon Smyth} \seealso{ \code{\link{normexp.fit}} An overview of background correction functions is given in \code{\link{04.Background}}. } \examples{# See normexp.fit} \keyword{models}