\name{geneclus} \alias{geneclus} \alias{geneclus.gagafit} \title{ Cluster genes into expression patterns. } \description{ Performs supervised gene clustering. Clusters genes into the expression pattern with highest posterior probability, according to a GaGa or MiGaGa fit. } \usage{ geneclus(gg.fit, method='posprob') } %- maybe also 'usage' for other objects documented here. \arguments{ \item{gg.fit}{GaGa or MiGaGa fit (object of type \code{gagafit}, as returned by \code{fitGG}). } \item{method}{For \code{method==1} samples are assigned to pattern with highest posterior probability, and for \code{method==1} to the pattern with highest likelihood (e.g. assuming equal a priori prob for all patterns)} } \details{ Each gene is assigned to the pattern with highest posterior probability. This is similar to routine \code{findgenes}, which also assigns genes to the pattern with highest posterior probability, although \code{findgenes} applies an FDR-based correction i.e. tends to assign more genes to the null pattern of no differential expression. } \value{ List with components: \item{d }{Vector indicating the pattern that each gene is assigned to.} \item{posprob }{Vector with posterior probabilities of the assigned patterns.} } \references{ Rossell D. GaGa: a simple and flexible hierarchical model for microarray data analysis. \url{http://rosselldavid.googlepages.com}. } \author{ David Rossell } \seealso{ \code{\link{fitGG}}, \code{\link{parest}} } \examples{ #Not run. Example from the help manual #library(gaga) #set.seed(10) #n <- 100; m <- c(6,6) #a0 <- 25.5; nu <- 0.109 #balpha <- 1.183; nualpha <- 1683 #probpat <- c(.95,.05) #xsim <- simGG(n,m,p.de=probpat[2],a0,nu,balpha,nualpha) # #ggfit <- fitGG(xsim$x[,c(-6,-12)],groups,patterns=patterns,nclust=1) #ggfit <- parest(ggfit,x=xsim$x[,c(-6,-12)],groups,burnin=100,alpha=.05) # #dclus <- geneclus(ggfit) #not use FDR correction #dfdr <- findgenes(ggfit,xsim$x[,c(-6,-12)],groups,fdrmax=.05,parametric=TRUE) #use FDR correction #table(dfdr$d,dclus$d) #compare results } % Add one or more standard keywords, see file 'KEYWORDS' in the % R documentation directory. \keyword{ htest } \keyword{ models }