\name{RankingWelchT} \alias{RankingWelchT} \alias{RankingWelchT-methods} \alias{RankingWelchT,matrix,numeric-method} \alias{RankingWelchT,matrix,factor-method} \alias{RankingWelchT,ExpressionSet,character-method} \title{Ranking based on the Welch t statistic.} \description{ Performs univariate (rowwise) Welch tests on a gene expression matrix. The Welch t statistic is a better alternative to the 'ordinary' t statistic in the two sample, unequal variances setting. } \usage{ RankingWelchT(x, y, type = "unpaired", pvalues = TRUE, gene.names = NULL, ...) } \arguments{ \item{x}{A \code{matrix} of gene expression values with rows corresponding to genes and columns corresponding to observations or alternatively an object of class \code{ExpressionSet}.} \item{y}{If \code{x} is a matrix, then \code{y} may be a \code{numeric} vector or a factor with at most two levels.\cr If \code{x} is an \code{ExpressionSet}, then \code{y} is a character specifying the phenotype variable in the output from \code{pData}.} \item{type}{Only the two sample case, \code{type="unpaired"} is possible. Otherwise, use \link{RankingTstat}. Variances are assumed to be unequal.} \item{pvalues}{Should p-values be computed ? Default is \code{TRUE}.} \item{gene.names}{An optional vector of gene names.} \item{\dots}{Currenly unused argument.} } \value{An object of class \link{GeneRanking}.} \author{Martin Slawski \cr Anne-Laure Boulesteix} \seealso{ \link{RepeatRanking}, \link{RankingTstat}, \link{RankingFC}, \link{RankingWilcoxon}, \link{RankingBaldiLong}, \link{RankingFoxDimmic}, \link{RankingLimma}, \link{RankingEbam}, \link{RankingWilcEbam}, \link{RankingSam}, \link{RankingShrinkageT}, \link{RankingSoftthresholdT}, \link{RankingPermutation}} \keyword{univar} \examples{ ## Load toy gene expression data data(toydata) ### class labels yy <- toydata[1,] ### gene expression xx <- toydata[-1,] ### run RankingWelch welchT <- RankingWelchT(xx, yy, type="unpaired") }