\name{GeneSetCollection-methods} \docType{methods} \alias{GeneSetCollection} \alias{GeneSetCollection-methods} \alias{GeneSetCollection,GeneSet,missing,missing-method} \alias{GeneSetCollection,list,missing,missing-method} \alias{GeneSetCollection,character,AnnotationIdentifier,CollectionType-method} \alias{GeneSetCollection,character,AnnotationIdentifier,CollectionIdType-method} \alias{GeneSetCollection,character,AnnotationIdentifier,PfamCollection-method} \alias{GeneSetCollection,character,AnnotationIdentifier,PrositeCollection-method} \alias{GeneSetCollection,character,AnnotationIdentifier,ChrlocCollection-method} \alias{GeneSetCollection,ExpressionSet,missing,CollectionType-method} \alias{GeneSetCollection,ExpressionSet,missing,CollectionIdType-method} \alias{GeneSetCollection,ExpressionSet,missing,KEGGCollection-method} \alias{GeneSetCollection,ExpressionSet,missing,GOCollection-method} \alias{GeneSetCollection,ExpressionSet,missing,PfamCollection-method} \alias{GeneSetCollection,ExpressionSet,missing,PrositeCollection-method} \alias{GeneSetCollection,ExpressionSet,missing,ChrlocCollection-method} \alias{GeneSetCollection,missing,AnnotationIdentifier,CollectionType-method} \alias{GeneSetCollection,missing,AnnotationIdentifier,CollectionIdType-method} \alias{GeneSetCollection,missing,AnnotationIdentifier,KEGGCollection-method} \alias{GeneSetCollection,missing,AnnotationIdentifier,GOCollection-method} \alias{GeneSetCollection,GOAllFrame,missing,GOCollection-method} \alias{GeneSetCollection,KEGGFrame,missing,KEGGCollection-method} \title{Methods to construct GeneSetCollection instances} \description{ Use \code{GeneSetCollection} to construct a collection of gene sets from \code{\linkS4class{GeneSet}} arguments, or a list of \code{GeneSet}s. } \usage{ GeneSetCollection(object, ..., idType, setType) } \arguments{ \item{object}{An argument determining how the gene set collection will be created, as described in the methods section.} \item{...}{Additional arugments for gene set collection construction, as described below.} \item{idType}{An argument of class \code{\linkS4class{GeneIdentifierType}}, used to indicate how the \code{geneIds} will be represented.} \item{setType}{An argument of class \code{\linkS4class{CollectionType}}, used to indicate how the collection is created.} } \section{Methods}{ \describe{ \item{ \code{signature(object = "GeneSet",idType="missing", setType="missing")} }{ Construct a gene set collection from one or more \code{GeneSet} arugments. } \item{ \code{signature(object = "list", idType="missing", setType="missing")} }{ Construct a gene set collection from a list of \code{GeneSet}s. } \item{ \code{signature(object="missing", idType="AnnotationIdentifier", setType="CollectionType")}, \code{signature(object="missing", idType="AnnotationIdentifier", setType="CollectionIdType")} }{ Construct a gene set collection of \code{CollectionType} entities (e.g., pathways for \code{KEGGCollection}, protein families for \code{PfamCollection}) implied by the map found in \code{annotation(idType)}. If \code{setType} is a \code{CollectionIdType} and \code{length(ids(setType))>0}, the gene set collection is filtered to contain only those sets implied by the ids. } \item{ \code{signature(object="character", idType="AnnotationIdentifier", setType="CollectionType")}, \code{signature(object="character", idType="AnnotationIdentifier", setType="CollectionIdType")} }{ Construct a gene set collection of \code{CollectionType} entities (e.g., pathways for \code{KEGGCollection}, protein families for \code{PfamCollection}) implied by the map found in \code{annotation(idType)}. Use only those identifiers in \code{object}. If \code{setType} is a \code{CollectionIdType} and \code{length(ids(setType))>0}, the gene set collection is filtered to contain only those sets implied by the ids. } \item{ \code{signature(object="character", idType="AnnotationIdentifier", setType="PfamCollection")} }{ Construct a gene set collection by mapping all values in \code{object} to \code{PfamIds} found in the \code{PFAM} map implied by \code{idType}. } \item{ \code{signature(object="character", idType="AnnotationIdentifier", setType="PrositeCollection")} }{ Construct a gene set collection by mapping all values in \code{object} to \code{ipi_ids} found in the \code{PFAM} map implied by \code{idType}. } \item{ \code{signature(object="character", idType="AnnotationIdentifier", setType="ChrlocCollection")} }{ Construct a gene set collection by mapping all values in \code{object} to chromosome, strand, and position information found in the map implied by \code{idType}. } \item{ \code{signature(object="ExpressionSet", idType="missing", setType="CollectionType")}, \code{signature(object="ExpressionSet", idType="missing", setType="CollectionIdType")} }{ Construct a gene set collection using the \code{annotation} and \code{featureNames} of \code{object} to identify elements for \code{CollectionType} gene sets (e.g., pathways for \code{KEGGCollection}, protein families for \code{PfamCollection}) implied by \code{object}. The gene set collection contains only those \code{AnnotationIdentifiers} found in \code{featureNames(object)}; if \code{setType} is a \code{CollectionIdType} and \code{length(ids(setType))>0}, the gene set collection is further filtered to contain only those sets implied by the ids. } \item{ \code{signature(object="ExpressionSet", idType="missing", setType="GOCollection")} }{ Construct a gene set collection using the \code{annotation} and \code{featureNames} of \code{object} to identify \code{GO} pathways implied by \code{object}. The map between \code{featureNames} and \code{GO} pathway identifiers is derived from the \code{GO2PROBE} table of the annotation package of \code{object}. The gene set collection contains only those \code{AnnotationIdentifiers} found in \code{featureNames(object)}. The \code{evidenceCode} of \code{GOCollection} can be used to restrict the pathways seleted to those with matching evidence codes. } \item{ \code{signature(object="ExpressionSet", idType="missing", setType="PfamCollection")} }{ Construct a gene set collection by mapping all values in \code{featureNames(object)} to \code{PfamIds} found in the \code{PFAM} map implied by \code{idType=AnnotationIdentifer(annotation(object))}. } \item{ \code{signature(object="ExpressionSet", idType="missing", setType="PrositeCollection")} }{ Construct a gene set collection by mapping all values in \code{featureNames(object)} to \code{ipi_id} found in the \code{PFAM} map implied by \code{idType=AnnotationIdentifer(annotation(object))}. } \item{ \code{signature(object="ExpressionSet", idType="missing", setType="ChrlocCollection")} }{ Construct a gene set collection by mapping all values in \code{featureNames(object)} to chromosome, strand, and position information found in the \code{CHRLOC} map implied by \code{idType=AnnotationIdentifer(annotation(object))}. } \item{ \code{signature(object="missing", idType="AnnotationIdentifier", setType="GOCollection")} }{ } \item{ \code{signature(object="GOAllFrame", idType="missing", setType="GOCollection")} }{ Construct a gene set collection containing all GO pathways referenced in the \code{GOALLFrame} provided. Each gene set only those \code{Identifiers} found in \code{GOALLFrame}. The \code{ontology} of each \code{GOALLFrame} GO ID will be included in the gene Set of that GO ID . } } } \seealso{ \code{\linkS4class{GeneSetCollection}}-class } \examples{ gs1 <- GeneSet(setName="set1", setIdentifier="101") gs2 <- GeneSet(setName="set2", setIdentifier="102") ## construct from indivdiual elements... gsc <- GeneSetCollection(gs1, gs2) ## or from a list gsc <- GeneSetCollection(list(gs1, gs2)) ## set names must be unique try(GeneSetCollection(gs1, gs1)) data(sample.ExpressionSet) gsc <- GeneSetCollection(sample.ExpressionSet[200:250], setType = GOCollection()) \dontrun{ ## from KEGG identifiers, for example library(KEGG.db) lst <- head(as.list(KEGGEXTID2PATHID)) gsc <- GeneSetCollection(mapply(function(geneIds, keggId) { GeneSet(geneIds, geneIdType=EntrezIdentifier(), collectionType=KEGGCollection(keggId), setName=keggId) }, lst, names(lst))) } } \keyword{methods}