\name{clusterSim} \alias{clusterSim} \title{Semantic Similarity Between Two Gene Clusters} \description{ Given two gene clusters, this function calculates semantic similarity between them. } \usage{ clusterSim(cluster1, cluster2, ont = "MF", organism="human", measure="Wang", drop= "IEA") } \arguments{ \item{cluster1}{A set of gene IDs. } \item{cluster2}{Another set of gene IDs. } \item{ont}{One of "MF", "BP", and "CC" subontologies.} \item{measure}{One of "Resnik", "Lin", "Rel", "Jiang" and "Wang" methods.} \item{organism}{One of "anopheles", "arabidopsis", "bovine", "canine", "chicken", "chimp", "ecolik12", "ecsakai", "fly", "human", "malaria", "mouse", "pig", "rat", "rhesus", "worm", "xenopus", "yeast" and "zebrafish".} \item{drop}{A set of evidence codes based on which certain annotations are dropped. Use NULL to keep all GO annotations.} } \value{ \item{sim}{Semantic Similarity.} } \seealso{ \code{\link{goSim}} \code{\link{mgoSim}} \code{\link{geneSim}} \code{\link{mgeneSim}} \code{\link{mclusterSim}} } \examples{ cluster1 <- c("835", "5261","241", "994") cluster2 <- c("307", "308", "317", "321", "506", "540", "378", "388", "396") clusterSim(cluster1, cluster2, ont="MF", organism="yeast", measure="Wang") } \references{ Wang et al.(2007) A new method to measure the semantic similarity of go terms \emph{Bioinformatics} (Oxford, England), 23:0 1274--81, May 2007. ISSN 1460-2059 \url{http://www.ncbi.nlm.nih.gov/pubmed/17344234} PMID: 17344234 P W Lord et al.(2003) Semantic similarity measures as tools for exploring the gene ontology \url{Pacific Symposium on Biocomputing} Pacific Symposium on Biocomputing, 2003:601-12, ISSN 1793-5091 \url{http://www.ncbi.nlm.nih.gov/pubmed/12603061} PMID: 12603061 } \keyword{ manip}