\name{discretizeExpressionValues} \alias{discretizeExpressionValues} \title{ Function to discretize gene expression data } \description{ Discretizes the gene expression data (float values) into \sQuote{Low}, \sQuote{Medium} or \sQuote{High} labels. } \usage{ discretizeExpressionValues(rmadataset, mfs, zeta = 0.5, overlapping = 2) } \arguments{ \item{rmadataset}{ \code{\link[Biobase:class.ExpressionSet]{ExpressionSet}} with numeric values containing gene expression values (rows) of samples belonging to different categories (columns).\cr The \code{\link[Biobase:class.ExpressionSet]{ExpressionSet}} also contains an \code{\link[Biobase:class.AnnotatedDataFrame]{AnnotatedDataFrame}} with metadata regarding the classes to which each sample belongs.} \item{mfs}{ \emph{Membership functions} to determine the discret value (linguistic label) corresponding to a given gene expression level. } \item{zeta}{ Threshold value which controls the activation of a linguistic label ('Low', 'Medium' or 'High').\cr The lower, the less posibilities of having genes with more than one assigned linguistic label.\cr \code{Default value = 0.5}. \code{Range[0,1]}. } \item{overlapping}{ Modifies the number of membership functions used in the discretization process.\cr Possible values: \enumerate{ \item \sQuote{Low}, \sQuote{Medium}, \sQuote{High}. \item \sQuote{Low}, \sQuote{Low-Medium}, \sQuote{Medium}, \sQuote{Medium-High}, \sQuote{High}. \item \sQuote{Low}, \sQuote{Low-Medium}, \sQuote{Low-Medium-High}, \sQuote{Medium}, \sQuote{Medium-High}, \sQuote{High}. } \code{Default value = 2}. } } \value{ Matrix containing discrete values according to the overlapping parameter after discretizing the gene expression values.\cr Includes an attribute \var{types} which determines the category of each sample. } \author{ Rodrigo Alvarez-Gonzalez\cr Daniel Glez-Pena\cr Fernando Diaz\cr Florentino Fdez-Riverola\cr Maintainer: Rodrigo Alvarez-Gonzalez <\email{rodrigo.djv@uvigo.es}> } \references{ F. Diaz; F. Fdez-Riverola; D. Glez-Pena; J.M. Corchado. Using Fuzzy Patterns for Gene Selection and Data Reduction on Microarray Data. 7th International Conference on Intelligent Data Engineering and Automated Learning: IDEAL 2006, (2006) pp. 1095-1102 } \keyword{manip}