\name{CMA-package} \alias{CMA-package} \alias{CMA} \docType{package} \title{Synthesis of microarray-based classification} \description{The aim of the package is to provide a user-friendly environment for the evaluation of classification methods using gene expression data. A strong focus is on combined variable selection, hyperparameter tuning, evaluation, visualization and comparison of (up to now) 21 classification methods from three main fields: Discriminant Analysis, Neural Networks and Machine Learning. Although the package has been created with the intention to be used for Microarray data, it can as well be used in various \code{(p > n)}-scenarios.} \details{ \tabular{ll}{ Package: \tab CMA \cr Type: \tab Package \cr Version: \tab 1.3.3 \cr Date: \tab 2009-9-14 \cr License: \tab GPL (version 2 or later) \cr } Most Important Steps for the workflow are: \describe{ \item{1.}{Generate evaluation datasets using \code{\link{GenerateLearningsets}}} \item{2.}{(Optionally): Perform variable selection using \code{\link{GeneSelection}}} \item{3.}{(Optionally): Peform hyperparameter tuning using \code{\link{tune}}} \item{4.}{Perform \code{\link{classification}} using 1.-3.} \item{5.}{Repeat 2.-4. based on 1. for several methods: \code{\link{compBoostCMA}}, \code{\link{dldaCMA}}, \code{\link{ElasticNetCMA}}, \code{\link{fdaCMA}}, \code{\link{flexdaCMA}}, \code{\link{gbmCMA}}, \code{\link{knnCMA}}, \code{\link{ldaCMA}}, \code{\link{LassoCMA}}, \code{\link{nnetCMA}}, \code{\link{pknnCMA}}, \code{\link{plrCMA}}, \code{\link{pls_ldaCMA}}, \code{\link{pls_lrCMA}}, \code{\link{pls_rfCMA}}, \code{\link{pnnCMA}}, \code{\link{qdaCMA}}, \code{\link{rfCMA}}, \code{\link{scdaCMA}}, \code{\link{shrinkldaCMA}}, \code{\link{svmCMA}}} \item{6.}{Evaluate the results from 5. using \code{\link{evaluation}} and make a comparison by calling \code{\link{compare}}} } } \references{ Slawski, M. Daumer, M. Boulesteix, A.-L. (2008) CMA - A comprehensive Bioconductor package for supervised classification with high dimensional data. \emph{BMC Bioinformatics 9: 439} } \author{ Martin Slawski \email{ms@cs.uni-sb.de} Anne-Laure Boulesteix \email{boulesteix@ibe.med.uni-muenchen.de} Christoph Bernau \email{bernau@ibe.med.uni-muenchen.de} Maintainer: Christoph Bernau \email{bernau@ibe.med.uni-muenchen.de}. } \keyword{multivariate}